Introduction: Dyslipidemia has been noted to play an integral role in the pathogenesis and progression of micro and macrovascular complications in Diabetes Mellitus (DM) patients. Lipid profile is the indicators of dyslipidemia.
Objectives: To evaluate the prevalence and pattern of dyslipidemia in type 2 DM patients.
Materials and Methods: This cross sectional study was conducted at Armed Forces Institute of Pathology (AFIP) from November 2014 to October 2015. The study included 300 type 2 diabetic patients belonging to the age group 30-59 years. Personal data and history of co-existing medical conditions were collected by data collection sheet and analyzed.
Results: Among 300 study subjects with type 2 DM the prevalence of dyslipidemia was 94% among them 19% had single dyslipidemia and 75% had multiple dyslipidemia. In this study, high level of total cholesterol (TC), triglycerides(TG) and Low Density Lipoprotein-Cholesterol (LDL-C) were found in 47.3%, 76.7% and 41.3% patients respectively. High Density Lipoprotein- Cholesterol (HDL-C) levels were found to be low in 60% patients.
Conclusion: The study revealed that dyslipidemia is very common in type 2 diabetic patients and the most common abnormality observed was increased serum TG level followed by decreased HDL-C level. So, patients with type 2 DM should be followed up with serum lipid profile regularly.
Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 177-179
Background: Women with polycystic ovarian syndrome (PCOS) have chronic anovulation and androgen excess not attributable to another cause. The fundamental pathophysiologic defect is unknown. Defects in LH secretion, LH/FSH ratio, amplitude of LH pulsations have been described; but the prevalence of these defects is not still clearly determined. Objective: To review the variable clinical presentations of polycystic ovarian syndrome. Materials and Methods: This observational study was carried out in Combined Military Hospitals of Jessore, Rangpur and Ghatail during November 2008 to June 2013. One hundred patients attending Gynaecology Outpatient Department (GOPD) having at least two of the following criteria hyperandrogenism, chronic oligo- or anovulation and ultrasonographic findings were selected. In all selected women LH and FSH serum levels were determined and LH/FSH ratios were calculated. Body mass index (BMI) was measured and was scored to classify their state of obesity. The collected data were compiled and arranged in tables and were subjected to analysis. Results: Most of the patients (92%) were 2030 years old. Chief complaint of the patients was infertility, either primary (72%) or secondary (28%). Eighty percent women had menstrual irregularities, 30% were hirsute, 71% cases were overweight and 17% were obese. On pelvic ultrasonogram polycystic ovaries were found in 20% cases and 80% had normal ovaries. Thirty percent patients had LH/FSH ratio between 2.12.9, 32% had >3 and it was found normal in 38% of cases. Conclusion: PCOS cannot be diagnosed by a single clinical or laboratory finding. The diagnostic approach should be based largely on history and physical examination. DOI: http://dx.doi.org/10.3329/jemc.v4i3.20944 J Enam Med Col 2014; 4(3): 156-160
Summary:Many organizations recommend the use of equations that provide a rapid method of assessing glomerular filtration rate (GFR) to facilitate the detection, evaluation, and management of chronic kidney diseases. Indeed, many clinical laboratories already report estimated GFR (eGFR) values whenever the serum creatinine level is measured. To compare the predictive equations for the measurement of GFR in Bangladeshi population, we measured GFR by creatinine clearance rate (
Background: In the last two decades, there has been increasing interest in the biology of vitamin D and a growing recognition is that vitamin D deficiency is common in tropical countries
25-OH vitamin D level in serum was estimated by electro-chemiluminescence on Cobas Elecsys e411 fully automated system on the day of collection. This method has been standardized against LC-MS/MS which in turn has been standardized to the NIST (National Institute of Standards and Technology, USA). The functional sensitivity was determined to be 4.01 ng/mL (CV 18.5%). Vitamin D deficiency is defined as 25(OH) D <50 nmol/L, insufficiency as 50-75 nmol/L and sufficiency as ≥75 nmol/L and toxicity >375 nmol/L. The definition of vitamin D status was based on the recommendation of the US Institute of Medicine (IOM) for vitamin D.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.