Background In patients with fixed orthodontics, the presence of orthodontic appliances causes dental plaque accumulation and hygiene problems. The purpose of this study was to evaluate the effect of Propolis and chlorhexidine mouthwashes on plaque and gingival indices in patients who are undergoing orthodontic treatment. Material and Methods In this triple blind study, in total, 37 patients aged from 15 to 35 years those who have been undergoing fixed orthodontic treatment were studied. After that, one of the mouthwashes that containing either Propolis or Chlorhexidine was randomly prescribed to patients. The patients were asked to use mouthwashes twice a day after brushing their teeth for three weeks consecutively. Indicators of plaque, gingival and periodontal status (PI, GI, CPI) were determined on Ramford teeth at the beginning and at the end of three weeks for each patient. Then the results were analyzed statistically. Results The difference between the values of plaque index ( P <0.001), gingival index ( P =0.006) and periodontal index ( P = 0.005) before and after administration of Propolis were statistically significant. The difference was also statistically significant for all three indexes of plaque ( P <0.001), gingival ( P =0.001) and periodontal ( P =0.003) before and after chlorhexidine mouthwash usage. The indices after using mouthwashes were not statistically significant different between two mouthwash groups. Conclusions It seems that Propolis mouthwash can be used as a suitable alternative in patients with fixed orthodontic treatment without the side effects of chlorhexidine mouthwash. Key words: Mouthwash, antimicrobial, Oral hygiene, Propolis, Dental plaque.
Background Malignant pleural effusion continues to be a common problem in patients with metastatic disease. This study was conducted to compare the efficacy and safety of bleomycin pleurodesis with povidone-iodine pleurodesis through a chest drain as palliative treatment for recurrent malignant pleural effusion. Methods Sixty cancer patients (36 males and 24 females) with recurrent malignant pleural effusion were enrolled in a prospective randomized trial. Thirty patients received povidone-iodine pleurodesis and 30 received bleomycin pleurodesis. Age, sex, side of the primary pathology, treatment outcome (recurrence and relapse time), and complications were analyzed. Results The mean age was 59.63 ± 7.68 years in the povidone-iodine group and 57.97 ± 9.27 years in the bleomycin group ( p = 0.452). The complications were identical in both groups: 2 (6.7%) patients had chest pain, 2 (6.7%) had fever, and one (3.3%) had hypotension. There was a good response to therapy in 20 (66.7%) patients in the bleomycin group and 25 (83.3%) in the povidone-iodine group ( p = 0.136). Conclusion The results of this study indicate that povidone-iodine should be considered as a selective chemical agent to perform pleurodesis in patients with recurrent malignant pleural effusion because it has the same effect but costs less than bleomycin.
Background: Neospora caninum is protozoan parasitic disease now described as the major cause of abortion and other reproductive issues. The aim of this study was to determine the seroprevalence of N. caninum in cattle breeds of the Sistan region, southeastern border area of Iran. Methods: Using an ELISA kit (ID.VET, France), the antibodies against N. caninum in cattle of Sistan was evaluated in 2016. Overall, 184 blood samples from apparently healthy cattle in the eastern border area of Iran Sistan were collected for assessment of antibodies against N. caninum. The values greater than or equal to 50%, were considered positive based on manufacture’s manual for ELASA kit. Results: 3.8% of 184 cattle have antibody against N. caninum. Chi-square test showed that the seroprevalence among Holsteins, Sistan and cross-breed was 9.4%, 0%, and 4.3%, respectively. No significant difference was observed among the breeds (P>0.05). The seroprevalence was decreased as the age of cow increased and there is no significant difference between the prevalence of N. caninum and different city area. No statistically significant relationship between the seroprevalence of N. caninum and history of abortion, lactation number and infertility was observed. Although there was no significant difference between the cattle breeds of the Sistan region all the Sistani cows were negative for the antibody against N. caninum. Conclusion: Infection rate with N. caninum in bovine population in Sistan region is very low. Environmental and management factors are the major causes, which influence the regional prevalence.
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