Alzheimer disease is associated with a low concentration of serum vitamin E in older people. However, necessary prospective cohort studies should be conducted to determine the risk of serum vitamin E for AD in the future.
A new Frisch-grid ionization chamber has been built to explore the appropriate choice of Frisch-grid. Detailed studies of the relationship between grid geometries and detector performance have been performed with an $$^{241}$$
241
Am source. This paper describes and compares the energy resolution of ionization chambers with parallel-wire and mesh grids of different grid parameters. Some specific recommendations for grid selection are provided based on the data currently available. To obtain optimal energy resolution, the operating voltage of the chamber must satisfy the condition of minimum electron collection on the grid with distinct geometries and parameters, respectively. Since there is no established theory applicable to both types of grids, we have devised a careful simulation procedure incorporating the COMSOL and Garfield++ codes to search for the conditions of the minimum electron collection on the grid. The simulation results fit the experimental data well, suggesting that this simulation method successfully predicts the suitable voltage setting when using a mesh grid or parallel wires grid as the shielding electrode.
Background: This study aims to assess the level and determinants of the general public's willingness to organ donation.Methods: We conducted a population-based cross-sectional study of 4261 participants in China. The primary outcome was the willingness to donate organs. Logistic regression modelling was used to determine the factors that affect willingness to donate organs.Results: Overall, the proportion of participants who showed a willingness to donate organs was 47.45% (95%CI: 0.46, 0.49) in this study. Logistic regression modelling showed participants from Western (OR=1.35, 95%CI=1.13-1.62) and Eastern China (OR=1.54, 95%CI=1.20-1.66) were more willing to donate organs compared with those from Central China. The odds of being willing to donate organs was higher in females than males (OR=1.34, 95%CI=1.17-1.55); and was higher in those participants with experience of organ donation (OR=1.57, 95%CI=1.12-2.20), experience of caring for organ transplant patients (OR=1.47, 95%CI=1.03-2.10), and those undertaking related voluntary activities (OR=1.68, 95%CI=1.45-1.94), than those without.
Conclusion:The general public's level of willingness to organ donation was not high in China. Geographical region, gender, experience of organ donation related activities, taking care of organ transplant patients and volunteering in related activities were independently associated with participants' willingness to donate organs.
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