One of the micronutrients that has attracted the most attention in relation to COVID-19 is vitamin D. Although several factors affect its sufficiency; it has been argued that an optimal diet can ensure the intake of micronutrients with effects on immune response. Therefore, in this work we aimed to evaluate the food intake quality of SARS-CoV-2 positive Mexican patients and some of the common factors related to vitamin D deficiency. We conducted a cross-sectional study in 40 SARS-CoV-2 positive patients. Serum samples and clinical parameters were collected. Micronutrient intake and food intake quality were assessed with a 24-h dietary recall and the Mini-ECCA v.2, respectively. Thirty-eight percent of the sample had a healthy food intake. The median 25(OH)D concentration was 22.7 ng/mL. A considerable insufficient intake of micronutrients with immunomodulatory effects such as vitamin D (p < 0.0001), vitamin E (p < 0.0001), and zinc (p < 0.0001) was shown. Patients with 25(OH)D sufficiency, defined as a concentration >30 ng/mL, had better food intake quality (p = 0.02) and an intense physical activity (p = 0.03). In conclusion, a better level of food intake quality and intense physical activity are associated with 25(OH)D sufficiency in SARS-CoV-2 positive Mexican patients.

Objectives: The principal aim of this study was to identify whether the Newcastle Satisfaction with Nursing Scales (NSNS) could be used on cancer patients. Methods: This was a descriptive, cross-sectional study carried out on cancer patients (n = 298). Results: We found that a majority of cancer patients were around 50 years old (hospitalized patients [HP]: 49.5 ± 14.9; chemotherapy outpatients [COP]: 49.4 ± 12.7), were female (HP: 74%; COP: 63.5%), and had received education at least up to elementary level (HP: 70%; COP: 80%). Breast cancer was the principal type of cancer (>34%) in both groups (HP and COP). The groups were comparable in age, sex distribution, place of origin, educational qualification, and type of cancer. Among HP, the experience and satisfaction scales of the NSNS showed good internal consistency (n = 235, α >0.9, r > 0.7), while among COP, only the satisfaction scale showed good internal consistency (n = 62, α = 1.00). Most patients’ perceptions (level of satisfaction) of hospitalization and chemotherapy services were positive (98% and 97%, respectively). Conclusion: An NSNS instrument specifically designed for ambulatory care cancer patients is necessary for it to be useful in assessing cancer patients' perception of nursing care. This will help improve the quality of care in Mexico. The presence of cancer by itself could modify the patients’ satisfaction level. Further large-scale studies are required to inves- tigate the patients’ perceptions of nursing care using the NSNS on different cancer patient groups. Keywords: Spanish satisfaction tool; hospital; patient satisfaction; oncology nursing; health care evaluation mechanisms.

Background In Mexico, motorcycle use is increasingly prevalent owing to the availability and low fuel consumption of the vehicle. With the increasing number of motorcycle users, the rate of injuries and mortality due to road traffic accidents has also increased. Objective The study aimed to describe the epidemiological profile of injured motorcyclists treated in a third-level hospital, who were involved in traffic accidents in Guadalajara's Metropolitan Area and Zapotlanejo municipality. Methods We realized a logistic regression model, where we included all variables with p<=0.25, they had three or less response options became in dummy variables for facilitate the analysis and we took as confounders factors either variables that modify up to 10% the value of Odd Ratio. Results In our study, we examined 180 injured motorcyclists. The factors that increases risk of severe injury at Metropolitan Zone of Guadalajara and Zapotlanejo’s town were as follows: the motorcycle was not functioning properly prior to the incident (OR 76.89, 2.08-2839.25), the motorcyclist consider had committed any traffic infraction at the time of the event (OR 6.88, 1.30-36.26), the injured live in Metropolitan Zone of Guadalajara (OR 7.58, 1.15-50.17), driving a motorcycle when the driver did not know if the vehicle was “salvage” or not (OR 113.84, 9.13-1419.96) and as protectors factors, we found that a person drove a motorcycle with brand not Italika (OR 0.06, 0.008-0.41) and the road traffic occurred by line road or intersection “+”(OR 0.10, 0.02-0.61). Conclusion This information allowed to observe that exist elements of motorcyclist, and the motorcycle and environment that increases or reduced severity injuries in this group, most important when they did not have a health insurance.

This study aimed to adapt the Work-Health Balance questionnaire (WHBq; (Gragnano, Miglioretti, Frings-Dresen, & de Boer, 2017) into Spanish and to provide evidence for its factorial structure, reliability, and validity. WHBq comprises 17 items with three scales: Work-Health Incompatibility (WHI), Health Climate (HC) and External Support (ES). It was applied to a sample of Mexican workers (n =316). Confirmatory factor analysis revealed that the three-factor model replicating the original structure provided good fit (CFI = 0.950; SRMR = 0.051; RMSEA = 0.069). The reliability of each factor and the whole questionnaire were satisfactory (α and ω higher than 0.70). The AVE was lower than 0.50 only for ES. Solutions to this problem are discussed. Concurrent and differential validity was examined with external criteria. The WHBq in its Spanish version shows good psychometric properties and theoretically consistent relationships with external variables. These findings provide support for its use as a valid and reliable tool in Mexico. El objetivo de este estudio fue hacer una adaptación cultural del cuestionario del balance trabajo-salud (WHBq; (Gragnano et al., 2017) al idioma español y proporcionar evidencia mediante el análisis factorial, la confiabilidad y validez. Este instrumento se compone de tres escalas: Incompatibilidad trabajo-salud (WHI), clima de salud (HC) y apoyo externo (ES), con un total de 17 ítems. Este se aplicó a una muestra de trabajadores mexicanos (n = 316). El análisis factorial confirmatorio reveló un modelo de tres factores reproducido en la estructura original, el cual mostró un buen ajuste (CFI = 0.950; SRMR = 0.051; RMSEA = 0.069). La confiabilidad de cada factor y del cuestionario en su totalidad fue satisfactorio (ω mayor a 0.70). El AVE fue inferior a 0.50 solo en ES. Se discuten las soluciones para este problema. La validez de constructo se evaluó por criterio externo. El WHBq en su versión al español mostró adecuadas propiedades psicométricas y su relación teórica consistente con variables externas. Con estos resultados se confirma que este instrumento es una herramienta válida y confiable para su uso en México.

Rheumatoid arthritis (RA) is an autoimmune inflammatory joint disease with complex pathogenesis associated with cytokine dysregulation. Macrophage migration inhibitory factor (MIF) plays a role in systemic inflammation and joint destruction in RA and could be associated with the secretion of other immune-modulatory cytokines such as IL-25, IL-31, and IL-33. For the above, our main aim was to evaluate the IL-25, IL-31, and IL-33 secretion from recombinant human MIF (rhMIF)-stimulated peripheral blood mononuclear cells (PBMC) of RA patients. The rhMIF and lipopolysaccharide (LPS) plus rhMIF stimuli promote the secretion of IL-25, IL-31, and IL-33 (p < 0.05) from PBMC of RA patients. The study groups, the different stimuli, and the interaction between both showed a statistically significant effect on the secretion of IL-25 (p < 0.05) and IL-31 (p < 0.01). The study of the effect of the RA patient treatments and their interaction with the effect of stimuli did not show an interaction between them. In conclusion, our study generates new evidence for the role of MIF in the secretion of IL-25, IL-31, and IL-33 and its immunomodulatory effect on RA.

Mayor (TDM) puede presentarse durante el inicio de la menopausia, variando su prevalencia de acuerdo a diferentes factores de riesgo clínicos y sociodemográficos; presentándose una mayor asociación al existir alteraciones en la sintomatología menopaúsica. Ante esto, se buscará determinar el riesgo para desarrollar TDM al presentar alteraciones en la sintomatología menopaúsica. Metodología: Es un diseño transversal analítico que incluyó a 252 mujeres iniciando su menopausia (48±1.7 años), atendidas en centros de salud de Guadalajara, Jalisco. Las variables analizadas fueron antecedentes sociodemográficos, utilizando el Inventario de Depresión de Beck para identificar el TDM y la Escala de Valoración de la Menopausia para determinar alteraciones en los principales dominios sintomatológicos de la menopausia. Se realizaron análisis descriptivos y de asociación por medio de Odds Ratio (OR), aplicando finalmente una regresión logística. Resultados: La prevalencia de TDM fue de 40.5%, teniendo asociación con el antecedente de uso de anticonceptivos y con el agravamiento en la sintomatología menopaúsica. El análisis ajustado determinó que hay más riesgo de presentar TDM cuando existen alteraciones en los dominios sintomatológicos, tales como en el somático (OR 3.96, IC95% 1.58-9.95), el urogenital (OR 4.29, IC95% 2.13-8.65) y el psicológico (OR 13.55, IC95% 3.97-46.30). Conclusión: La presencia de alteraciones en la sintomatología menopaúsica se encuentra asociado con un mayor riesgo de presentar TDM, sobre todo si el dominio psicológico está afectado, por lo cual es necesario que el personal de salud identifique estas alteraciones y brinde un manejo temprano en esta etapa de la vida.

IntroductionTraffic events are one of the five leading causes of mortality in Mexico. Pedestrians are one of the main road users involved in such incidents and have the highest mortality rate, which is regularly analysed in relation to vehicles and pedestrians, but not the built environment. The purpose of this study was to analyse the elements of the road system organisation that influences the mortality rate of pedestrians hit by motor vehicles in the Guadalajara Metropolitan Area.MethodWe designed a case and control study in which the cases were sites where a pedestrian died during 2012. The controls were sites close to where the death occurred, as well as those with road infrastructure characteristics similar to those where the events took place. We obtained the pedestrian data from the death certificates and assessed some of the environmental elements of the road sites. A logistic regression analysis was used to estimate OR; 95% CI.ResultsRoad system factors related with pedestrian mortality in close locations were: the presence of bus stops on intersections in one street or both, and road system features, such as the presence of traffic islands, vehicle flow and pedestrian flow.ConclusionsAccording to the urban network theory and multiple theory, the final elements resulted as risk factors due to a fault in connectivity between the nodes. A temporal analysis of urban features will help urban planners make decisions regarding the safety of pedestrians and other road users.