Coronavirus disease 2019 (COVID-19) named by the WHO as a result of the global public health emergency. COVID-19 is caused by a new coronavirus named as novel coronavirus (2019-nCOV). From the first case reported in December 2019 it is now a pandemic situation and a major public health emergency. The COVID-19 transmission rate is very high, infecting two to three persons on average with contact to an already infected person. There is a need for the health system, specially in developing countries such as in Pakistan, to combat such a novel disease by rapid, accurate, and high quality diagnostic testing in order to screen suspected cases and also surveillance of the disease. A rapid, accurate and low-cost diagnostic point-of-care device is needed for timely diagnosis of COVID-19 and is essential to combat such outbreaks for compelling preventive measures against the disease spread. This review is to highlight the importance of point-of-care diagnostics device for robust and accurate diagnosis of COVID-19 in physician offices and other urgent healthcare-type settings and encourage academics and stake holders towards advancement in order to control outbreaks and develop the public health surveillance system.

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The family Solanaceae consists of many plants, one of them is Solanum viarum Dunal. This plant contains chemical constituents like Solasodine which is found in many plants of Solanaceae family. The Solasodine have many medicinal properties and used as cardiotonic, antifungal, antispermatogenic, antiandrogenic, immunomodulatory, anticancer, anti-inflammatory, antinociceptive and as antipyretic. The study was carried out to ascertain analgesic and antipyretic activity of ethanolic extract of Solanum viarum Dunal leaves. The ethanolic extract of Solanum viarum Dunal leaves at 100 and 200mg/kg oral single dose treatment show a significant difference (p<0.0001) in reaction time in terms of analgesic activity before and after treatments comparable to standard drug Diclofenac (10mg/kg body weight) and also reduced the elevated body temperature induced by Brewer's yeast. The extract also shows significant (p<0.0001) decrease in elevated body temperature at 100 and 200mg/kg comparable to standard drug Paracetamol (150mg/kg body weight).

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