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The qualitative condition and development of the environment in the Košice region is clearly affected by any activity within social development. Anthropogenic activities, especially in the manufacturing industry, negatively impact on the individual components of the environment in particular emissions of contaminants into air, water, soil and rock environment, also due to accidents, waste production and also by remote of agricultural land. It should be noted that among various components of the environment are very tight feedback and mutually influence each other and therefore any decrease in quality of one component as a result of contaminants introduction leading to disruption of ecological balance is automatically reflected in other components of the environment. Increasing the intensity of anthropogenic activities is taking place on one side an increase of environmental burdens through the issuance of a wide range of contaminating substances and exploitation through natural resources which is a manifestation of deterioration of the productivity of the country, of its hygienic and aesthetic values, and on the other side increase in economies may foster environmental protection to finance any corrective measures or to help prevent pollution by using more environmental technologies. The paper deals with the evolution and analysis of the mentioned problems within the Košice region.