ResumoO artigo analisa a intolerância e suas manifestações nas sociedades modernas, em particular nos espaços de trabalho. Vários autores vinculam a intolerância a raízes biológicas, outros a processos sociais. O artigo dialoga criticamente com esses referenciais e propõe uma perspectiva dialética apontando que a intolerância nas relações de trabalho tem se expressado por meio de atitudes violentas, discriminatórias, irônicas, doentias e recorrentes, que configuram o assédio laboral estimulado pela forma de o capitalismo organizar o trabalho na contemporaneidade.
Fruto de uma reflexão conjunta realizada pelas autoras a partir de diferentes experiências no contato com trabalhadores mulheres e homens portadores das Lesões por Esforços Repetitivos (L.E.R.s). Contatos estes, que foram possíveis pelo atendimento desses trabalhadores encaminhados pelos Centros de Referência de Saúde do Trabalhador para os serviços ambulatoriais da UNIFESP/ EPM, pelas pesquisas que as autoras estão desenvolvendo com trabalhadores do Hospital São Paulo e pela prática médica no Sindicato dos Trabalhadores nas Indústrias Químicas, Plásticas, Cosméticos e Similares de São Paulo.O fio condutor do trabalho é a incorporação da categoria gênero para compreender o impacto diferenciado das L.E.R.s na vida das mulheres e dos homens, no mundo das novas tecnologias que criam novas(os) trabalhadoras(es), novas(os) doentes e excluídas(os). Esta abordagem desvendou a esfera esquecida da subjetividade na vida desses trabalhadores.O estudo apontou que adquirir L.E.R. é trazer empresa e os seus processos produtivos para o interior da casa, onde o sentimento de culpa se reforça, com implicações e interferências nas relações afetivas do cotidiano.
This study is the result of a joint reflection by the authors starting from different experiences of contact with women and men workers suffering of RSI. These contacts were made possible by the attendance of these workers forwarded by the Centros de Referência de Saúde do Trabalhador (Worker's Health Reference Centers) to the out-patient services of UNIFESP/EPM, by the authors ongoing research with women and men workers of Hospital São Paulo and by the medical practice of the Chemical, Plastic, Cosmetics and Similar Industry Workers Union of the State of São Paulo. The guiding thread of the work is the inclusion of the category of gender to understand the different impacts of RSI in the lives of women and men in the world of the new technologies that create new workers, new diseases and new excluded people.This approach has revealed the forgotten field of subjectivity in the lives of these workers.The study pointed out that to acquiring RSI is bringing the company and its productive processes into the home, where the feelings of guilt are reinforced, with implications and interferences in the daily affective relationships
The relationship between self-compassion and well-being and health (e.g. a lower proneness for eating-related disturbances) is well stressed in the literature. However, the specific contribution of self-compassionate attributes, actions, and body compassion remains scarcely studied. The main aim of the present study was to examine whether the link between self-compassionate attributes and disordered eating attitudes and behaviours is mediated by self-compassionate actions and body compassion, in a sample of 299 Portuguese women from the general population. The tested model explained 44% of eating psychopathology's variance and presented excellent fit indices. The most interesting contribution of this study was the suggestion that the ability to act in accordance with self-compassionate attributes is associated with higher levels of body compassion, that is, an attitude of appreciation, acceptance, warmth toward body-related thoughts, perceptions and feelings, which reflects in a lower susceptibility to adopt disordered eating attitudes and behaviours. These results seem to offer an important contribution for research and clinical practice by supporting the importance of including strategies to develop self-compassionate skills and body compassion competencies in prevention and treatment programs in the area of eating psychopathology. Level of evidence Level III, evidence obtained from a well-designed cohort.
Hypopigmentation is a progressive dermatological condition caused by a reduction in the skin pigment, melanin. Its treatment is considered a challenge due to the lack of a highly efficient single therapy. Currently, the main treatments include photochemotherapy, application of corticosteroids and immunosuppressants, and laser. Khellin-based gel-in-oil emulsions appear as a promising alternative since they ensure a concentration of the drug, a natural furanochromone, at the desired location, skin surface. Khellin promotes repigmentation as it forms a dark colored complex after solar irradiation. The aim of this study was the development and characterization (e.g., rheological behaviour, droplet size, tackiness, adhesion and spreadability) of three topical gel-in-oil emulsions prepared with different emollients, formulated through a cold emulsification process, and suitable for the incorporation of khellin. In vitro studies were performed to evaluate the drug release and permeation profiles across artificial membranes and excised human skin, respectively, using Franz-type vertical diffusion cells. The W/O emulsions developed showed macroscopic appearance, shear-thinning behavior with a mean droplet size from 3.28 to 4.28 μm, suitable for topical application. In vitro studies revealed permeation values of about 1% of khellin across the stratum corneum, making these gel-in-oil emulsions promising for preclinical and clinical studies. The cold process, being an easy and low energy production method, represents an innovative strategy to produce khellin-based gel-in-oil emulsions to treat patients with hypopigmentation.
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