No abstract

In order to assess the cardiovascular autonomic nervous functions in patients with fetal type Minamata disease (FMD), we investigated blood pressure (BP), and conducted time and frequency domain analysis of heart rate variability (HRV). Subjects were 9 patients in Meisuien recognized as FMD, and 13 healthy age matched control subjects. HRV and BP were assessed after subjects rested in a supine position for 10 minutes. Electrocardiographic (ECG) data were collected for 3 minutes during natural breathing. Time domain analysis (the average of R-R intervals [Mean RR], standard deviation of R-R intervals [SD RR], coefficient of variation [CV]), and frequency domain analysis by fast Fourier transformation (FFT) (power of low frequency [LF] and high frequency [HF] component, expressed in normalized units[nu]) were then conducted. In the time domain analysis, the mean RR of the FMD group was significantly lower than that of the control group. Neither SD RR nor CV showed significant differences between the two groups, but both tended to be lower in the FMD group. In the frequency domain analysis, the HF component of the FMD group was significantly lower than that of the control group. Pulse pressure (PP) was significantly lower in the FMD subjects. These findings suggest that parasympathetic nervous dysfunction might exist in FMD patients, who were exposed to high doses of methylmercury (MeHg) during the prenatal period. Decrease of PP might be due to degenerative changes of blood vessels driven by exposure to high doses of MeHg.

Depression in elderly persons may increase the risk for prevalent disability. It is very important for elders to prevent and reduce depression for improving the quality of their life and physical function.

No abstract

According to work observation studies, daily exposure time to vibration was 160-210 min. ISO5349 predicted that this exposure level would be associated with a high risk of HAVS in workers. We found no clear evidence of VWF. There may be several reasons why no worker exhibited VWF: (1) warmer work conditions, (2) younger and less experienced workers, (3) seasonal changes in work operations, and (4) healthy worker effect. On the other hand, 5-10% of rock drill operators might be suffering from moderate HAVS which was sensori-neural type dominant. There may be some characteristic features of HAVS among quarry workers in the tropical area. (J Occup Health 2005; 47: 165-170)

To describe changes in activities of daily living (ADL) of community-dwelling Beijing elderly people, observed for 8 years, and to identify the demographic characteristics that predict the functional change. Four sets of interview data from 1992 to 2000 were used to evaluate changes among Beijing elderly aged 55 years and over. Results revealed that prevalence of disability increased from 3.9% to 7.1% during the 8 years of follow-up with the average increasing rate of disability was 0.41% per year. Meanwhile an increasing likelihood of recovery from disability is observed with age and time. Women, aged 75 or more, experienced higher disability than men though it was in the opposite for younger ages. In addition, certain demographic subgroups (such as women, unmarried, illiterate and living in non urban area) appeared to be at higher risk for ADL impaired. The patterns of ADL change is in both the direction of improvement and declination. Demographic variables emerged as a significant predictor in estimating functional outcomes. Furthermore, it is recommended that the demarcation factor for the evaluation of ADL should be 75 years of age.

Two surveys, one in winter the other in summer time, examined the skin problems of the entire manual workers (N=148) from 11 small-to-medium sized fiber-glass reinforced plastics (FRP) factories located in Kyushu, Japan. The workers were exposed to unsaturated polyester resin, including styrene and auxiliary agents such as cobalt naphthenate, hardeners such as methyl ethyl ketone peroxides, glass fiber and dust including shortened glass fiber and plastic particles. Eightyseven workers (58.8%) reported having skin problems (mainly itching or dermatitis) since they started to work in FRP manufacturing and 25 workers had consulted a physician because of their skin problems; one worker was forced to take sick leave because of his severe dermatitis. History of allergic diseases and shorter occupational period (duration of employment) in a FRP factory were associated with greater probability of having a history of work-related skin symptoms. Workers in factories where dust-generating and lamination sites were located in different buildings were significantly less likely to have a history of skin problems than those in factories where the two sites were located in the same building. Of the 67 workers examined in both seasons closed to double the prevalence of dermatitis was found in summer (23.3%) than winter (13.4%).

Objective: Clarify the relation between the complaints of wheelchair users and the vibration characteristics of the wheelchair, to improve wheelchair comfort and design.Methods: The questionnaires were distributed to 33 wheelchair users directly by the experimenter in order to identify the causes of complaints from wheelchair vibrations that they experienced. The vibration transmissibility of wheelchairs of ten subjects was measured to clarify the causes of complaints of wheelchair vibration according to the ISO 10326-1 standard in the laboratory using a broadband random vibration spectrum with a frequency-weighted vibration magnitude of 0.1 ms 2 r.m.s. over the frequency range from 0.2 to 100 Hz. Each vibration exposure lasted 60 seconds.Results: The following findings were clear from the questionnaire results; (i) the vibration from the wheelchair affected psychological comfort; (ii) the effects of different riding surfaces were important engineering issues affecting wheelchair ride comfort; (iii) the wheelchair users felt the vibration during wheelchair usage at locations on the neck, lower back and buttocks; (iv) vertical vibration was the most noticeable vibration from the wheelchair to each participant's body. The following findings were clear from the results of the transmissibility measurement of the wheelchair; (i) the resonance frequency-ranges of the transmissibility of the wheelchair showed significant differences between the subjects; (ii) intra-subject variability from three repeated transmissibility measurements was small; (iii) the first resonant frequency occurred approximately 5 to 7 Hz and the second resonant frequency occurred at around 8 Hz and the third resonant frequency occurred approximately 13 to 15 Hz; (iv) the magnitude of the peak transmissibility varied from 1.3 to 2.6.Conclusion: From the comparison of the results of questionnaires and the transmissibility measurement of the wheelchair, the resonance frequency-ranges of the maximum vibration transmissibility of the manual wheelchairs were consistent with the frequency-ranges of the body parts of the causes of the complaints of wheelchair users. In addition, from these experimental results, it was suggested that the main point for improving a wheelchair user's comfort was to reduce the wheelchair seat vibration transmissibility at around 8 Hz and also to design wheelchair stiffness and damping characteristics to minimize vibration transmission at specific frequencies at body locations that caused the discomfort reported by wheelchair users.