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Owa and Owa inquired about the serologic tests of the 3 neonates and the treatment of neonates with COVID-19. The serologic tests for SARS-CoV-2 were not available until the end of February 2020. Currently, only 6 infected neonates have been reported in China. Four mildly infected neonates improved with primary care. Of 2 critical cases in China, 1 was the third patient in our article, and another neonate with congenital heart disease (6.9-mm atrial septal defect) presented with pneumonia and cardiac insufficiency. The neonate improved rapidly with antibiotics, inotropic therapy, and fluid management. None of the infected neonates received antiviral therapy.Verd et al raised the issue of whether mothers with COVID-19 should continue breastfeeding. Viral nucleic acid for SARS-CoV-2 has not been detected in breast milk thus far. However, the neonates born to an affected mother are at great risk of COVID-19 owing to close contact and should be separated from mothers and fed by formula initially. As our protocol suggested, the isolated mothers should keep pumping to maintain breast milk. 3 Considering the virus may be excreted into the milk during the incubation period, donor milk and breast milk can be considered for use after being screened for SARS-CoV-2. 3 Mimouni et al questioned the criteria used to diagnose COVID-19 pneumonia. In our study, 3 neonates with COVID-19 had not been reported in other cohorts before publication. Patients 1 and 2 were born February 3, 2020, and February 5, 2020, respectively. Patient 1 was admitted to the neonatal intensive care unit owing to lethargy and fever (37.6 °C) at day 3 of life (February 5, 2020). His procalcitonin level (PCT) was 0.090 ng/mL (normal range, ≤0.05 ng/mL). Patient 2 experienced lethargy, vomiting, and fever (37.7 °C), and laboratory test results showed leukocytosis, lymphocytopenia, and an elevated creatine kinase myocardial band. Although no respiratory symptoms were observed and chest images showed infiltrates, the 2 neonates were diagnosed as having symptomatic neonatal COVID-19 based on the exposure history and positive SARS-CoV-2 test result. 3,4 Currently, less than 10 confirmed neonatal cases have been reported. Therefore, the full clinical picture of neonatal COVID-19 remains uncertain.Hijikata et al, Abu Raya et al, and Vecchio pointed out that the serial serologic tests were helpful to diagnose congenital COVID-19. We do agree that viral or serologic test results cannot confirm the intrauterine SARS-CoV-2 infection. However, at the early phase of the COVID-19 epidemic in China, the testing methods for SARS-CoV-2 were limited. Initially, real-time fluorescence PCR was only available for SARS-CoV-2 using nasopharyngeal and oropharyngeal specimens. At present, both serological testing and RT-PCR can be performed; yet, no more neonates with early-onset COVID-19 have been identified with the control of the COVID-19 epidemic in China.We are concerned about the neurologic outcomes of neonates with COVID-19 or born to infected mothers. The study from Zhu et...
The present work addresses the importance of data analysis to understand the COVID-19 pandemic and its impact in the Midwest region of Brazil. The need for an accurate and correct analysis is highlighted to ensure the adequate allocation of resources in the fight against the disease. The text also describes the steps involved in conducting research on the coronavirus, including proposal, literature review, data quantification, and statistical analysis. According to the Ministry of Health, COVID-19 is caused by the SARS-CoV-2 coronavirus and can range from asymptomatic infections to severe controlled conditions. Most patients (about 80%) may be asymptomatic, while about 20% of cases may require hospital care and approximately 5% may require ventilatory support. The disease is caused by a virus that lives in the controlled tract of bats and may have undergone a mutation process to install itself in the human body. The main symptoms are fever, shortness of breath, dry or secret cough, and sore throat. So far, there is no specific vaccine for the new coronavirus, but at least eight types of vaccines are being made in humans in search of the most efficient immunization. Keywords: Coronavirus, database, perception, solution. Results are presented using line graphs and tables, providing a clear picture of the current situation and informing the public on how to identify and seek treatment for the disease.
Câncer possui várias doenças malignas, no qual ocorre o crescimento desordenado de células, que podem se espalhar em tecidos adjacentes ou órgãos. O câncer pode ter diversas causas externas e internas e a interação destes fatores dão origem a este. A prevenção do câncer acontece por meio de ações que reduzem as chances de ter a doença. Evitar a exposição aos fatores de risco, conduzindo um modo de vida saudável é a prevenção primária, enquanto que a prevenção secundária é realizada por meio do tratamento de doenças pré-malignas. Desta forma, é de grande importância a discussão sobre este assunto. Sendo assim, este livro retrata sobre fatores relacionados a diversos tipos de cânceres, assim como índice de mortalidade e atuação de profissionais da saúde na oncologia.Em nossos livros selecionamos um dos capítulos para premiação como forma de incentivo para os autores, e entre os excelentes trabalhos selecionados para compor este livro, o premiado foi o capítulo 5, intitulado "ASPECTOS GENÉTICOS RELACIONADOS AO CÂNCER DE MAMA".
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