The combination of desloratadine plus montelukast is effective in the treatment of CU. It may therefore be a valid alternative in patients with relatively mild CU, in view of its efficacy and the lack of adverse events.
As the standard series detected a relatively low proportion of occupational allergic contact dermatitis, it is not adequate to recognize an occupational allergic contact dermatitis, certain supplementary series should also to be tested. However, even if such occupational series are used, we remain likely to continue to underestimate the frequency of occupational allergic contact dermatitis, because workers come into contact with a large number of substances that are often unknown.
Sir, and a positive CAP to latex (6.22 kU/l). By history, the latex allergy was induced by hemodialysis. She did not manifest Patients undergoing chronic hemodialysis can, although rarely, develop hypersensitivity reactions to substances used in dialysis dermatitis or pruritus, nor a history of atopy. None of the other subjects had latex sensitivity based on skin tests or CAP. equipment (1, 2). The aim of our study was to evaluate the frequency of latex and rubber chemical hypersensitivity in Eighty-three patients (53.9%) accepted to undergo the patch test. A history of atopic disease was reported by 6 subjects patients undergoing long-term hemodialysis. (7.2%), pruritus by 35 (42.2%) and dermatitis by 22 (26.5%). Sixteen patients (19.3%), exhibited positive patch tests to PATIENTS AND METHODS rubber antigens (Table I). For 9 of them, the rubber allergy We enrolled 154 consecutive hemodialysis patients (66 women and 88 was considered clinically relevant, as these patients had previmen). The median time of dialysis was 53Ô 44 months, with a range ously had episodes of allergic contact dermatitis following of 1± 205 months. Skin-prick tests were performed with a standardized exposure to the rubber allergens. However, it was not possible commercial extract of non-ammoniated latex (StallergeÁ nes, Paris, to assess whether the sensitivity to the rubber chemicals was France) and with glove extracts prepared as previously reported (3). Brie¯y, twenty 1 cm2 (400 mg total weight) freshly cut glove pieces
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.