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A breathalyser has been used to measure blood alcohol levels at short intervals to produce an absorption curve which we have shown is reproducible. Changes in the rate of absorption which reflect changes in gastric emptying times produced by metoclopromide and propantheline have been demonstrated. The breathalyser technique described appears to offer a simple method of studying the effects of drugs on the rate of gastric emptying.

The relation between blood levels and urinary excretion of amphetamine under controlled acidic and under fluctuating urinary pH values using [ 14C]amphetamine