Adjunctive treatment with antidepressants in bipolar depression was associated with substantial risks of threshold switches to full-duration hypomania or mania in both acute and long-term continuation treatment. Of the three antidepressants included in the study, venlafaxine was associated with the highest relative risk of such switching and bupropion with the lowest risk.

This paper examines family experiences with the efficiency of ASD diagnosis. Children were age 8 or younger with ASD (n = 450). Outcomes were delay from first parent concern to diagnosis, shifting diagnoses, and being told child did not have ASD. Predictors were screening, travel distance, and problems finding providers. Logit models were used to examine associations. Screening was associated with reduced delay in diagnosis; problems finding providers were associated with greater delay. Screening, travel distance, and delay in diagnosis were associated with shifting diagnoses and being told child did not have ASD. Physician and parent training in communication and addressing mental health professional shortages and maldistribution may improve the diagnosis experiences of families of children with ASD.

Low-income mothers develop depressive symptoms at higher rates than the general population, adding to the existing risk that economic hardship places on their infants and toddlers. Emphasizing a few key intervention targets, an approach that is especially relevant to mothers when depressive symptoms compromise their energy and concentration, can improve interventions with populations facing adversity. The goal of this study was to identify contextual risk factors that significantly contributed to depressive symptoms and that, in combination with depressive symptoms, were associated with compromised parenting. Using baseline data from 251 ethnically diverse mothers from six Early Head Start programs in the Northeastern and Southeastern US, who were recruited for a clinical trial of an in-home intervention, Belsky's ecological framework of distal to proximal levels of influence was used to organize risk factors for depressive symptoms in hierarchical regression models. Under stress, mothers of toddlers reported more severe depressive symptoms than mothers of infants, supporting the need for depressive symptom screening and monitoring past the immediate postpartum period. Multivariate models revealed intervention targets that can focus depression prevention and intervention efforts, including helping mothers reduce chronic day-to-day stressors and conflicts with significant others, and to effectively handle challenging toddler behaviors, especially in the face of regional disciplinary norms. Presence of a live-in partner was linked to more effective parenting, regardless of participants' depressive symptom severity.

Objective A higher rate of depressive symptoms is found among mothers of children with disabilities compared to other parents. However, there is a lack of study of mothers with children <3 years of age participating in Early Intervention (EI) programs. This study aims to more fully describe the extent of mood disorders in these mothers including estimated prevalence, severity and factors associated with maternal mental health, using gold standard clinical diagnostic and symptom measures, and test models associating depressive symptoms with contextual factors and child behavior. Methods A cross-sectional study was conducted with 106 women who had at least one child enrolled in EI. Mothers were interviewed and completed reliable, valid measures to evaluate mental health, health status, family conflict, parent-child interaction, self-efficacy, social support, child behavioral problems, hardship, endangerment, and child disability. Descriptive statistics and multivariate analyses were performed. Results We found 8 % of participants met all criteria for a Major Depressive Episode (MDE) with 44 % of the sample reporting a past episode and 43 % endorsing recurrent episodes. Using the CES-D to assess depressive symptom severity approximately 34 % of mothers screened in a clinically significant range. Using linear regression to predict severity of current depressive symptoms demonstrated that current depression severity was primarily predicted by poorer maternal health status, lower self-efficacy and past MDE (p < 0.05). Conclusions for practice A brief assessment of maternal mood, health and self-efficacy are important factors to assess when evaluating how to support mothers of children in EI.

Activation among Latino parents was improved with MePrEPA, which can be readily incorporated in current practices by mental health clinics. Future work should replicate findings in a large number of sites, adding behavioral measures and distal impacts while examining MePrEPA's effects across settings and populations.

Objective: The objective of this study was to establish the psychometric properties of reliability and validity of the «Maslach Burnout Inventory-Human Services Survey» (MBI-HSS). Methods: The work was conducted by a process of translation and back-translation of the original instrument, instrument adaptation, translation and adaptation of the application manual, pilot study, and implementation of the adapted version of the instrument with 314 health professionals in Cali, according to the guidelines of the International Test Commission (ITC). Results: The results showed that the scale has good internal consistency (a=0.767); however, the dimension of «depersonalization» has the lowest internal consistency (a=0.518). Regarding validity, in comparing between the factor structure of the modified scale with the original version, we identified that the size of the validated version largely coincides with that of the original version; in the dimension of emotional fatigue, item 6 is excluded because it will be part of the depersonalization scale, items 15 and 21 were also excluded given their poor discriminatory ability. Conclusion: It is necessary to overcome the stability problems of the MBI-HSS depersonalization subscale in health professionals and reformulate the response options to make them more understandable for professionals within the Colombian context.

Background Despite the fact that airborne pollen is an important factor in precipitating asthma attacks, its implication in increases of epidemic asthma in usual meteorological conditions has not been reported. A study was undertaken to estimate the relationship between various types of aeroallergens and seasonal epidemic asthma in the region of Madrid, Spain. Methods A caseecontrol study was carried out in individuals aged 4e79 years who received emergency healthcare for asthma during 2001 in a base hospital covering a population of 750 000 inhabitants of Madrid. A skin prick test was performed with grass pollen, plantain pollen, olive pollen, cypress pollen, plane tree pollen, dust mites and Alternaria and the prevalence of skin reactivity was compared between subjects with asthma requiring emergency care for asthma within (cases) and outside (controls) the seasonal epidemic period. Data were analysed using logistic regression adjusting for age and sex. Results The response rate was 61.7% for cases (n¼95) and 51.6% for controls (n¼146). The OR of sensitisation to grass pollen for cases compared with controls was 9.9 (95% CI 4.5 to 21.5); plantain pollen: 4.5 (95% CI 2.5 to 8.2); olive pollen: 7.3 (95% CI 3.5 to 15.2); plane tree pollen: 3.6 (95% CI 2.0 to 6.4); cypress pollen: 3.5 (95% CI 2.0 to 6.2); dust mites: 1.1 (95% CI 0.6 to 1.9); Alternaria: 0.9 (95% CI 0.5 to 1.9). The association with grasses was maintained after adjusting simultaneously for the remaining aeroallergens (OR 5.0 (95% CI 1.5 to 16.4)); this was the only one that retained statistical significance (p¼0.007). Conclusions These results suggest that allergy to pollen, particularly grass pollen, is associated with the epidemic increase in asthma episodes during the months of May and June in the Madrid area of Spain.

The goals of this study were to explore the prevalence of childhood family violence (CFV) (both suffered and witnessed) among male batterers in treatment, and to analyze the specific psychological profile of those perpetrators with CFV. A sample of 1,421 men recruited from a specialized batterer treatment program was assessed. A description of the sociodemographic, violence, and psychopathological characteristics of the sample was carried out. Moreover, a comparison of all the variables studied between batterer men with and those without CFV was conducted. The results showed that 35.2% ( n = 500) of the sample reported having been victims of CFV (67.2% of them directly suffered abuse, and 32.8% witnessed violence between their parents, mainly from father to mother). Batterers with CFV presented with more irrational beliefs both about women and about violence as a strategy to cope with everyday difficulties. Moreover, they had significantly higher scores than batterers without CFV on all psychopathological symptoms as assessed by the SCL-90-R, as well as on most of the STAXI-2 subscales. In the logistic regression analysis, the main variables related to having a history of CFV were low education level, voluntary access to the program, having a previous psychiatric history, being an immigrant, having children, and presenting a greater number of psychopathological symptoms. According to these results, batterers with CFV showed a higher severity in most of the variables studied than those without CFV. Consequently, these findings highlight the importance of tailoring batterer treatment programs to their specific characteristics, particularly those regarding childhood victimization.