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Amyloidosis is a rare disease. Nodular cutaneous amyloidosis is the rarest clinical form of cutaneous amyloidosis. It may be associated with a systemic disease. We report an exceptional case of amyloidosis associated with myeloma, with a double atypical localization: Well-defined papulo-nodules of the base of the penis; Vertebral amyloidosis causing spinal cord compression. The association of nodular skin lesions to a myeloma should evoke the diagnosis of amyloidosis.

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Allergic contact dermatitis (ACD) is a common skin condition that causes significant disruption of a country's economy as a result of rising school and work-related absenteeism besides the persistent medical expenses. 1. To determine the demographic profile of ACD patients 2. To determine the source of allergens and its preferred sites of involvement 3.To evaluate the patch test and its relationship with various allergens.   This study enrolled 60 patients diagnosed with ACD attending the Department of Dermatology, Venereology and Leprosy Vinayaka Mission Medical College & Hospital, Salem and relevant history, clinical examination and patch test were done using standard protocols. Data were entered in Microsoft Excel [2007] and analyzed using Statistical Package for Social Sciences [SPSS] version 21.0 Chicago, USA. The mean age of the subjects were 40.4±13.7 years. The males and females were affected in the ratio of 3:2. Housewives (28.3%) hugely contracted ACD followed by agriculturists (20.0%), masons (15.0%), students (11.7%), professionals (10.0%) cement factory workers (8.3%), and others (6.7%).  Nickel sulphate and potassium dichromate were the most common allergens found.  The patch test was positive for 51.7% of the subjects while it was negative and doubtful for 35.0% and 13.3% respectively. India being a developing nation, has seen rising rates of occupational dermatosis in the venture of its rapidly expanding urbanization. Hence vibrant protection measures at all  occupational levels in addition to the stricter implementation of regulatory control and warranting public education about the safety protocols has to be exercised in all set ups.

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The association between dermatology and psychiatry has been well known from mid-nineteenth century and is evolving since then as a consequence of overwhelming psychiatric morbidities among the persons with certain dermatoses. This study is intended to unveil such relationship and to establish gamut of opportunities directed to enhance the quality of life of such individuals. 1) To assess the socio-demographic profile of patients diagnosed with Acne Vulgaris (AV) and Psoriasis. 2) To grade the severity of disease using Pillsbury scale for AV and Psoriasis Area and Severity Index (PASI) for Psoriasis. 3) To assess the psychological burden of the disease by using Dermatological Life Quality Index (DLQI). 4) To determine the effect of dermatological treatment if any and to assess its impact on DLQI score. This study enrolled 116 patients diagnosed with AV and Psoriasis attending the Department of Dermatology, Venereology and Leprosy Vinayaka Mission Medical College & Hospital, Salem and questions regarding socio-demographic profile, disease severity (PASI and Pillsbury scale), quality of life (DLQI) were measured and compared before and after intervention. Data were entered in Microsoft Excel [2007] and analyzed using Statistical Package for Social Sciences [SPSS] version 21.0 Chicago, USA This study was dominated by females (twice) and the subjects averaged 27.6 ± 12.9 years of age. The patients with moderate and severe forms of AV were the maximum (96.3%). Similarly the patients with moderate and severe psoriasis comprised two-third. Both the sub-groups has averaged larger effect of the respective disease condition downgrading their quality of life (DLQI score 20.1± 3.2 for AV and 23.4 ± 2.4 for psoriasis) although post-treatment scores declined by significant margins (DLQI score 7.9± 2.1 for AV and 9.1 ± 2.3 for psoriasis) As there exist positive correlations between earlier treatment onset and advancing quality of life, expediting the implementation of psychological assessment for the potential dermato-psychiatric illnesses has to be scaled up in all dispensaries.

Background: Women with congenital heart disease who become pregnant form an important subgroup of pregnancy cardiac disorders. The additional stress of pregnancy represents a further challenge.Methods: This was a retrospective study. Patient records between 2011and 2015 pertaining to 77 pregnant women with congenital heart diseases were analysed.Results: There was only one patient aged more than 35 years. The age of the others ranged from 18 to 35 years. The mean age was 24 years. There was a slight rural preponderance with 43 (55.8%) from rural areas. Majority 49 (63.5%) belonged to lower middle socioeconomic status. 71 (92.2%) had NYHA functional Class I. Two patients of Class II had worsening of their status. There were no cases of Atrial Fibrillation and only 2(2.6%) had CCF.ASD closure was the commonest procedure done24 (31.2%). There were 6 (7.8%)cases of device closure of PDA and no cases of VSD. Anemia and GDM were seen in 4 (5.2%). The commonest period of gestation at delivery was 37-40 in 64 (83.1%). ASD was the commonest type of lesion 42 (54.5%). 36 (46.8%) had spontaneous labour and there were 18 23.4%)caesarians. Previous LSCS was the commonest indication for LSCS. Full term normal vaginal delivery was seen in 45 (88.2%). Majority of the newborns 30 (39%) had a birth weight in the range 2.6-3.0 kgs.Conclusions: There is a significant burden of Heart disease with pregnancy afflicting young rural women and those from lower socioeconomic levels. Higher level of specialised care minimizes poor maternal and fetal outcomes.