This paper considers the different technique of estimation of crowd densities, an important part of the problem of automatic crowd monitoring and control. A new technique based on texture description of the images of the area under surveillance is proposed.
One of the proposed mechanisms of homocysteine toxicity in human is the modification of proteins by the metabolite of Hcy, homocysteine thilolactone (HTL). Incubation of proteins with HTL has earlier been shown to form covalent adducts with ε-amino group of lysine residues of protein (called N-homocysteinylation). It has been believed that protein N-homocysteinylation is the pathological hallmark of cardiovascular and neurodegenerative disorders as homocysteinylation induces structural and functional alterations in proteins. In the present study, reactivity of HTL towards proteins with different physico-chemical properties and hence their structural and functional alterations were studied using different spectroscopic approaches. We found that N-homocysteinylation has opposite consequences on acidic and basic proteins suggesting that pI of the protein determines the extent of homocysteinylation, and the structural and functional consequences due to homocysteinylation. Mechanistically, pI of protein determines the extent of N-homocysteinylation and the associated structural and functional alterations. The study suggests the role of HTL primarily targeting acidic proteins in eliciting its toxicity that could yield mechanistic insights for the associated neurodegeneration.
-Researchers have largely focused on analyzing citation links from one scholarly work to another. Such citing sentences are an important part of the narrative in a research article. If we can automatically identify such sentences, we can devise an editor that helps suggest when a particular piece of text needs to be backed up with a citation or not. In this paper, we propose a method for identifying citing sentences by constructing a classifier using supervised learning. Our experiments show that simple language features such as proper nouns and the labels of previous and next sentences are effective features to identifying citing sentences.
The study suggests that kaempferol showed attenuation in sepsis-induced acute lung injury in mice through suppression of oxidative stress, iNOS, and ICAM-1 pathways.
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