Half of obese Russian inhabitants are metabolically healthy. At the same time, metabolic abnormalities were detected in one third of non-obese participants with a shift to male gender.
В большинстве европейских стран и США ожидае-мая продолжительность жизни у женщин в среднем на 6 лет больше, чем у мужчин, в России данный показатель превышает 10 лет [1]. По данным мировой статистики, основные различия в уровне заболеваемости между муж-чинами и женщинами приходятся на трудоспособный возраст, и, как результат, в возрастной группе 15-59 лет смертность мужчин в нашей стране трехкратно превы-
21. Kelder JC, Cramer MJ, Wijngaarden van J. The diagnostic value of physical examination and additional testing in primary care patients with suspected heart failure.
Objective:
To identify associations of fecal calprotectin with cardiovascular risk factors including vascular damage in population-based sample.
Design and method:
77 patients without cardiovascular diseases from population-based sample were randomly invited and signed informed consent. All patients underwent a questionnaire (eating habits, physical activity, smoking, alcohol consumption, stress, anxiety and depression, quality of life, EFPQ), anthropometry, blood pressure and pulse measurement, laboratory examination (biochemical blood test, lipids, fecal calprotectin), vascular examination (carotid ultrasound, applanation tonometry by SphygmoCor, volume sphygmomanometry by Vasera).
Results:
Results The analysis included 77 patients, 33 (42.8%) males with mean age 52 [43;59] years, and 44 (57.2%) females with mean age 60.5 [47;66] years. The results of the linear regression analysis adjusted for sex and age of the level of calprotectin are presented in Table 1.
Table 1 Results of linear regression analysis of fecal calprotectin levels.
Conclusions:
Fecal calprotectin as intestinal wall inflammation marker has been associated with dietary patterns, metabolic disorders, behavioral habits such as a tendency to depression and increased alcohol consumption, as well as carotid atherosclerosis.
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