A 22-year-old woman who presented with a tumour of the upper eyelid with clinical, histological, immunohistochemical and ultrastructural features of a Merkel cell carcinoma is reported. This is a unique case of Merkel cell carcinoma in such a young patient. This neuroendocrine tumour is typically found in the elderly. It can grow rapidly, has the potential for local recurrence and early metastatic spread. The authors recommend wide resection of the primary site, which proved effective in this case.
In order to determine and compare the behavior of chromed catgut and polyglecaprone 25 sutures, 49 female rats anesthetized with ether were submitted to laparotomy, cystotomy and cystorrhaphy with separate stitches using catgut for group C and polyglecaprone 25 for group E. When the bladders were observed 3, 7, 15, 30 and 50 days after suture application, stone formation was observed in 6 group C animals (p = 0.0058), with two stones (one per stitch) in 3 of them. No stones were detected in group E bladders. Microscopy revealed a similar course for the healing process and crystals were observed only in group C (p = 0.0159). We conclude that: 1) the tissue behavior of chromed catgut and polyglecaprone 25 sutures is similar, 2) catgut sutures produce lithiasis in 46.15% of the bladders sutured with it up to 50 days after surgery (p = 0.0058), and 3) polyglecaprone 25 sutures do not produce lithiasis up to 50 days after surgery
A 28-year-old white male with AIDS-C3 staging, presented with an extensive hemorrhagic dark mass localized in the left orbit. No other ophthalmic findings were disclosed. Ultrasonography and computed axial tomographic scans showed orbital involvement. Orbital Kaposi's sarcoma is a rare finding and only a few cases have been reported. Systemic examination revealed other lesions suggestive of disseminated mucocutaneous Kaposi's sarcoma, oral candidiasis, membranous esophagitis and granulomatous hepatitis. Eyelid incisional biopsy disclosed Kaposi's sarcoma. Despite intensive chemotherapy progression was aggressive with a fatal outcome.
This study investigates the rule that repeating cytological preparations on liquid-based cytology improves sample adequacy, diagnosis, microbiological, and hormonal evaluations. We reviewed 156 cases of pap-stained preparations of exfoliated cervical cells in two slides processed by DNA-Cytoliq System. After sample repeat/dilution, limiting factors affecting sample adequacy were removed in nine cases and three unsatisfactory cases were reclassified as satisfactory. Diagnosis was altered in 24 cases. Of these, the original diagnosis in 15 was atypical squamous cells of undetermined significance; after the second slide examination, diagnosis in 5 of the 15 cases changed to low-grade squamous intraepithelial lesion, 3 to high-grade squamous intraepithelial lesion, and 7 to absence of lesion. Microbiological evaluation was altered, with Candida sp. detected in two repeated slides. Repeat slide preparation or dilution of residual samples enhances cytological diagnosis and decreases effects of limiting factors in manually processed DIGENE DCS LBC.
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