Orbital Kaposi's Sarcoma in Acquired Immunodeficiency Syndrome

Abstract

A 28-year-old white male with AIDS-C3 staging, presented with an extensive hemorrhagic dark mass localized in the left orbit. No other ophthalmic findings were disclosed. Ultrasonography and computed axial tomographic scans showed orbital involvement. Orbital Kaposi's sarcoma is a rare finding and only a few cases have been reported. Systemic examination revealed other lesions suggestive of disseminated mucocutaneous Kaposi's sarcoma, oral candidiasis, membranous esophagitis and granulomatous hepatitis. Eyelid incisional biopsy disclosed Kaposi's sarcoma. Despite intensive chemotherapy progression was aggressive with a fatal outcome.

Kaposi sarcoma in unusual locations

“…In one case with widely disseminated KS, tumor involving the choroid of both eyes was identified at autopsy [ 46 ]. A case of widely disseminated AIDS-associated KS localized in the patient's orbit has been previously described [ 94 ]. Despite intensive chemotherapy, progression in this patient was aggressive with a fatal outcome.…”