Aim: To determine the potential of propolis extract and BBG combination on the quantity of fibroblast growth factor 2 (FGF-2), vascular endothelial growth factor (VEGF), and osteoblasts in the preservation of tooth extraction socket on days 3 and 7. Settings and Design: Laboratory in vivo reseach using animal model. Materials and Methods: Fifty-six Cavia cobaya were divided into eight groups containing seven animals in each group. The extraction socket on the lower left incisor was filled with polyethylene glycol (PEG) at a concentration of 2% (Groups I and II) as a control; active materials consisted of propolis extract and PEG (Groups III and IV); active materials consisted of BBG and PEG (Groups V and VI); and active materials consisted of propolis extract, BBG, and PEG (Groups VII and VIII). Then, an examination was done using immunohistochemistry to perform an expression of VEGF, FGF2, as well as histology of osteoblasts. Statistical Analysis Used: The statistical analysis performed using a one-way ANOVA and Tukey's honestly significant difference test. Results: Propolis extract, BBG and PEG had the most significant result related to the formation of FGF2, VEGF, and osteoblasts. Conclusion: The combination of propolis extract with BBG and PEG in socket preservation is effective in increasing the expression of FGF2, VEGF, and osteoblasts.
Background: Tooth extraction is a procedure frequently performed in the field of dentistry that can cause alveolar bone resorption during the healing process. Therefore, preservation of sockets is necessary to maintain alveolar bone which represents one of the important factors in the successful manufacture of dentures. A combination of propolis extract and bovine bone graft (BBG) can accelerate bone regeneration. Purpose: The purpose of this study was to determine the effects of a combination of propolis extract and BBG on the quantity of fibroblasts, osteoblasts, and osteoclasts in the tooth extraction socket. Methods: 56 Cavia cobaya were divided into eight groups. The lower left incisor of each subject was extracted and induced with polyethylene glycol (PEG), propolis extract + PEG, BBG + PEG, combination of propolis extract + BBG + PEG at a concentration of 2% active substance. Experimental subjects were sacrificed on days 3 and 7. Histopathological examination with a microscope at 400x magnification was conducted to calculate the quantity of fibroblasts, osteoblasts, and osteoclasts. Statistical analysis was performed by one-way ANOVA and Tukey HSD tests. Results: The highest average quantity of fibroblasts and osteoblasts and the lowest average quantity of osteoclasts occurred in the group to which a combination of propolis extract and BBG had been administered on both days 3 and 7. According to the statistical analysis results, all the treatment groups recorded a significant difference in the quantity of fibroblasts, osteoblasts, and osteoclasts with a p value: 0.000 (p<0.05). Conclusion: A combination of propolis extract and BBG can increase the quantity of fibroblast and osteoblast cells, while reducing the number of osteoclast cells in tooth extraction sockets treated with 2% concentration of the active substance.
Background: Esthetically and functionally successful full mouth rehabilitation requires careful attention and me-ticulous treatment planning. Successful restoration in a patient with anterior crossbite and a partially edentulous situation can be challenging especially when bilateral posterior segment teeth is missing. Combination restora-tion using attachment retained removable partial denture (RPD) and removable partial overdenture (RPO) is such kind of treatment modality in prosthodontics. Purpose: This study was to provide an overview of a case about full mouth rehabilitation in anterior crossbite and posterior bite collapse patient. Case: A 64-year-old female pa-tient came to Prosthodontic Department of RSGMP Universitas Airlangga to have dentures replacing her missing teeth with aesthetic issue on her anterior teeth in order to eat well and be more confident. The patient wants to change her smile into new smile with acceptable aesthetic and function. Management: Diagnostic wax-up was made to capture the right occlusal vertical dimension (OVD) in centric relation (CR) that will be used in the first stage of full mouth rehabilitation, followed by management of the remaining teeth by endodontic and periodontal intervention by crown lengthening. Then, definitive restorations were made by maxillary attachment retained RPD with splint four anterior crowns and mandibular RPO with two single crowns on the lower teeth to correct anterior crossbite and posterior bite collapse. Conclusion: Patient had a satisfactoryly aesthetic and functional results with new occlusion using maxillary attachment retained RPD and mandibular RPO.
One of the most important consideration for patients in dental treatment is esthetics. It presents a great challenge when teeth (particularly anterior teeth) have to be immediately replaced following removal of teeth structure. Immediate denture is the answer to restore esthetics and functional (mastication, speech and deglutition) purpose. A 48-year-old male patient came to Department of Prosthodontic Clinic, Universitas Airlangga Dental Hospital to fix his old dentures because there were missing and mobile anterior teeth. The patient did not want to undergo edentulous phase and wanted to be able to chew properly and fix his teeth appearance. Immediate partial denture treatment was given as a solution to the patient. The problematic teeth were extracted and endodontically treated. Afterwards the immediate partial denture, made using heat cured acrylic, was inserted directly in one visit. The patient was satisfied with the resulting immediate denture. The denture was able to deliver esthetics, function and comfort.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.