Purpose:To evaluate diffusion-weighted imaging (DWI) for detection of pelvic lymph node metastasis in patients with cervical and uterine cancers.
Materials and Methods:Fifty patients scheduled for pelvic lymph node dissection were enrolled for 3T magnetic resonance imaging (MRI) using a single-shot echo-planar DWI technique, body-phased array coil, b ϭ 0, 1000 s/mm 2 . We measured short/long-axis diameters, mean apparent diffusion coefficient (ADC) values of all identifiable nodes, relative ADC values between tumors and nodes, and utilized their cutoff values to validate the diagnostic accuracy internally. Histopathologic results served as the reference standard.
Results:The relative ADC values between tumor and nodes were significantly lower in metastatic than in benign nodes (0.06 vs. 0.21 ϫ 10 Ϫ3 mm 2 /s, P Ͻ 0.001; cutoff value 0.10 ϫ 10 Ϫ3 mm 2 /s). Compared to conventional MRI, the method combining size and relative ADC values resulted in better sensitivity (25% vs. 83%) and similar specificity (98% vs. 99%). The smallest metastatic lymph node detected by this method measured 5 mm on its short axis.
Conclusion:The combination of size and relative ADC values was useful in detecting pelvic lymph node metastasis in patients with cervical and uterine cancers.
Lithium Sulfur (Li/S) chemistries are amongst the most promising next-generation battery technologies due to their high theoretical energy density. However, the detrimental effects of their intermediate byproducts, polysulfides (PS), have to be resolved to realize these theoretical performance limits. Confined approaches on using porous carbons to entrap PS have yielded limited success. In this study, we deviate from the prevalent approach by introducing catalysis concept in Li/S battery configuration. Engineered current collectors were found to be catalytically active towards PS, thereby eliminating the need for carbon matrix and their processing obligatory binders, additives and solvents. We reveal substantial enhancement in electrochemical performance and corroborate our findings using a detailed experimental parametric study involving variation of several kinetic parameters such as surface area, temperature, current rate and concentration of PS. The resultant novel battery configuration delivered a discharge capacity of 700 mAh g−1 with the two dimensional (2D) planar Ni current collectors and an enhancement in the capacity up to 900 mAh g−1 has been realized using the engineered three dimensional (3D) current collectors. The battery capacity has been tested for stability over 100 cycles of charge-discharge.
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