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The present study was conducted on the incidence studies of the canine parvovirus (CPV) infection from different parts of Andhra Pradesh, India. A total of three hundred and forty two (n=342) canine parvovirus suspected clinical faecal samples of different age group of dogs from both vaccinated and non-vaccinated animals were collected. The faecal samples were preliminarily screened by haemagglutination assay and further confirmation by employing polymerase chain reaction (PCR). Dogs of age group below four months were more susceptible for CPV infection at a higher rate (77.59%) and were predominantly seen in males. PCR technique was found to be more sensitive in confirming the CPV infection (68.42%) than haemagglutination assay (20.67%).