Background and Objective:The osteoporosis is becoming public health problem in India and neighboring Asian countries. As the environmental risk factors for osteoporosis in women are similar in these countries, the study was planned to compare risk factors for osteoporosis in postmenopausal women in Asian countries.Materials and Methods:A systematic literature search was done in August 2015. The period included for this search was from January 2005 to December 2014. The search was done for India and neighboring countries. The final analysis was done on the studies from India, China, Korea, and Japan. The literature search was done in PubMed and Google Scholar using key words, “Osteoporosis” and “Menopause” and “Risk factor.”Results:The pooled prevalence for the osteoporosis in postmenopausal women is 41%, but in India alone, it is 53%. Various risk factors are studied in China as compared to other countries. Adequate calcium intake and various exercises were found to be useful modifiable factors. Other factors like age, height, and postmenopausal status cannot be modified.Conclusion:Adequate calcium and Vitamin D intake and combinations of various exercises can be considered as preventive measures for osteoporosis in postmenopausal women.
Objective:To compare the cure rates of oral single dose of metronidazole (2 g), tinidazole (2 g), secnidazole (2 g), and ornidazole (1.5 g) in cases of bacterial vaginosis.Materials and Methods:This was a prospective, comparative, randomized clinical trial on 344 Indian women (86 women in each group) who attended a gynecology outpatient department with complaint of abnormal vaginal discharge or who had abnormal vaginal discharge on Gynecological examination but they did not complaint of it. For diagnosis and cure rate of bacterial vaginosis, Amsel's criteria were used. Statistical analysis was done by Chi-square test of proportions. The cure rate was compared considering metronidazole cure rate as gold standard.Results:At 1 week, the cure rate of tinidazole and ornidazole was 100% and at 4 weeks, it was 97.7% for both drugs (P<0.001). Secnidazole had cure rate of 80.2% at 4 weeks (P=NS). Metronidazole showed a cure rate of 77.9% at 4 weeks, which is the lowest of all four drugs.Conclusion:Tinidazole and ornidazole have better cure rate as compared to metronidazole in cases of bacterial vaginosis.
Purpose/Introduction:Osteoporosis is a multifactorial and slowly emerging global health problem. The lifetime risk of dying from hip fracture is same as that from breast cancer. One out of three women between age group of 50-60 years in India suffers from osteoporosis. Indian women have an early age of onset of osteoporosis as compared to western counterparts. There is need for early diagnosis, identification of high-risk groups and prevention and treatment of osteoporosis in the Indian context. The aim of this study was to review the literature published in last decade and compare the research in India with that in rest of the world.Materials and Methods:Research articles with key words menopausal, osteoporosis and bone mineral density were searched in Pubmed from January 2004 to December 2013. Articles were categorized according to year, place and objective of the studies.Results:In India more articles were published in year 2010-11 (53.3%), while outside the country a uniform distribution of studies was observed throughout the last decade. Objective of research was screening and diagnosis (36.7%) and risk factor identification (40%) in most of the Indian studies as compared to rest of the world. Research publications on prevention and treatment of osteoporosis are less in India (20%).Conclusion:Research focusing on diagnosis, prognosis, prevention and treatment are needed in India.
While 60% of women experiencing recurring episodes of bacterial vaginosis (BV) with vaginal pH >or= 5 are depleted of resident probiotic lactobacilli, the remainder carry one or more strains of lactobacilli. Their ability to make D-lactic acid is, however, low (3.94 +/- 0.72 mM/L) compared to the D-lactic acid produced by strains from healthy vagina with vaginal pH approximately 4 (8.04 +/- 1.07 mM/L) culture supernatant of 0.5 McFarland concentration (P < 0.001).
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