While 60% of women experiencing recurring episodes of bacterial vaginosis (BV) with vaginal pH >or= 5 are depleted of resident probiotic lactobacilli, the remainder carry one or more strains of lactobacilli. Their ability to make D-lactic acid is, however, low (3.94 +/- 0.72 mM/L) compared to the D-lactic acid produced by strains from healthy vagina with vaginal pH approximately 4 (8.04 +/- 1.07 mM/L) culture supernatant of 0.5 McFarland concentration (P < 0.001).
This article reviews the findings of the Phase II clinical trial conducted in 80 women suffering from recurrent episodes of Vaginosis whose vaginal pH was above 5.0. Intravaginal intake every night for seven days of easily dispersible capsules containing either the Polyherbal wide spectrum action microbicide BASANT, or 3 × 10 9 bacilli of 3 selected meritorious Probiotics cured Vaginosis in 65%-70% of women. However, the intake of the Combination of the two was remarkably effective in curing 95% (19 out of 20) women, restoring fully healthy vagina.
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