Objective The objective of this study was to analyze the antifungal activity of citral, selected by screening natural products, against Candida albicans isolates from subjects who use dental prostheses. Methodology Screening of essential oils, including those from Mentha piperita L. (Briq), Origanum vulgare, and Zingiber officinale L., and the phytoconstituents citral and limonene, to select an appropriate natural product. Citral, which mediated the best antifungal response, was selected for biological assays. The minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) for citral and nystatin were determined by the microdilution method. Micromorphological analyses, time-kill curve, and modulation tests were performed. Results The MIC and MFC of citral were established as 32 μg/mL, consistent with fungicidal activity. The clinical strains were resistant to nystatin. Citral caused micromorphological alteration in the strains. In the time-kill curve, the growth of the clinical strain was reduction in growth equal to 3 log10 colony-forming units per milliliter after exposure to the MIC and MIC × 2 of citral for 2 h. Citral did not modulate the resistance of the studied strains to nystatin. Conclusion This study revealed the potential of citral as a fungicidal agent and highlighted the resistance of clinical strains of C. albicans to nystatin.
Implantes dentários realizados imediatamente após a exodontia contam com uma alta taxa de sucesso e permitem a reabilitação do paciente com uma quantidade menor de intervenções para a finalização do caso. O estudo em questão tem o objetivo de relatar um caso de uma paciente que foi submetida a técnica do implante imediato em área estética. Neste artigo é relatado um caso clínico de uma paciente do sexo feminino, jovem, onde houve a indicação de exodontia do elemento 11, incisivo central direito, e após a exodontia atraumática foi feita a instalação do implante dentário de forma imediata, entretanto, sem carga imediata. Foi utilizado enxerto ósseo Geistlich Bio-Oss® para preencher os espaços entre o implante e o alvéolo e para melhorar a qualidade dos tecidos moles foi feito enxerto de tecido conjuntivo concomitante. A reabilitação provisória da paciente consistiu na instalação de uma prótese adesiva, que permite a reabilitação provisória, sem colocar carga no implante recém instalado e sem realizar desgaste nos dentes adjacentes. Sabe-se que a estética do sorriso tem impacto direto na autoestima do paciente, já que os seres humanos são seres sociais que baseiam toda sua existência na comunicação e imagem, ter uma parte de destaque da face afetada negativamente pode trazer enormes prejuízos ao auto apreço e relações psicossociais. Desta forma, o uso desta técnica possibilitou a reabilitação da paciente de forma funcional e estética, tendo ganho em sua qualidade de vida.
Objective: To achieve a literature review on the impacts of COVID-19 on dentistry. Methods: Analysis of scientific articles contained in the LILACS and PubMed platforms that fulfill the informative purpose of the research. Results: The production of aerosols during dental procedures could be highlighted as the most dangerous agent, the literature recommends restricting the type of service only to emergencies and reducing the use of rotating instruments or cough-inducing equipaments. New protective measures must be taken, such as the type of PPE used and the frequency of asepsis of the workplace, since any surface that has been exposed to oral or pharyngeal secretions may contain a load of viral particles, an online triage is also recommended before any assistance. Due to the easy spreading of this disease and the possibility of asymptomatic patients, the current best measure is avoiding the execution of procediments. Conclusion: COVID-19 will be a milestone for the current generations of health professionals, it could also be an advance for use distance technologies and integration of new biosafety techniques.
Medicinal plants are an important source of curative substances for the treatment of diseases. Investigations are focusing particularly on medicinal plants used to treat affections of the oral cavity. Among these species, there is evidence of potential applications of Syzygium cumini to Dentistry. The objective of this systematized literature review was to synthesize the evidence on the antimicrobial activity of this plant, as well cite some as the traditional uses of its extracts for dental purposes. The data indicate that the extracts prepared from different parts of the plant have antibacterial and antifungal effects on different pathogenic microorganisms of the oral microbiota and/or those that can potentially cause oral diseases, demonstrating a promising therapeutic potential for indication and use in Dentistry to prevent and/or treat oral affections.
Limonene is the main component of citrus essential oils, and can reach a concentration of up to 96%. Popularly known for its potential therapeutic effects on the body, among these we point out its broad antimicrobial activity against various types of pathogens. Therefore, the purpose of this study was to address the antimicrobial and antifungal properties of limonene compared to microorganisms of interest in dentistry, based on a bibliometric study and literature review. The following databases were analyzed: PubMed, Google Scholar, SciELO and Science Direct, from which ten articles published between 2011-2021 were selected. Most of results indicate a satisfactory antimicrobial potential, besides providing important data and perspectives regarding the indication and clinical use, in addition to innovative therapeutic modalities for diseases that affect the oral cavity, such as tooth decay, periodontal disease and candidosis.
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