It has been widely documented that hemodialysis patients get a blocked secure response, that might result in a greater prevalence rate of viral diseases, according to Coronavirus epidemic 2019. . The point of this consider was to assess the recurrence of Covid -19 Immunoglobulin G (IgG) antibodies among hemodialysis patients. The current research included 90 hemodialysis patients (50 males and 40 female) who gone to Tikrit Teaching Hospital for the time from starting of December/2020 to the conclusion of May/2021. The Covid -19 -IgG was found in a higher rate in males than that in females (18.89% and 12.22% respectively). Also, non-significant relation was found between age and seropositivity for Covid -19 -IgG antibodies (p ≤ 0.05). Since patients receiving hemodialysis treatment are immunocompromised and can be at risk of infection of Covid -19.
Human Cytomegalovirus (HCMV) is a DNA virus of the Betaherpesvirinae subfamily and Herpesviridae family. HCMV is a leading cause of congenital infections throughout the world. This study was carried out in Kirkuk governorate from July 2017 to January 2018,aimed at studying there activity of anti-HCMV IgM to various specific HCMV antigens among 180 pregnant women attending hospitals, primary health care centers and some private medical laboratories. The pregnant women were examined for HCMV-IgM seroprevalence using Electro-chemo-luminescence(ECLIA) technique then examined their reactivity for specific HCMV antigens using line immune assay. The rates of HCMV-IgM seropositive were 22 (12.22 %). Regarding the reactivity of determined HCMV-IgM against various HCMV antigens, the rates 14 (63.63%), 13(59.09%), 21(95.45%), 15(68.18%), 21(95.45%) and 16(72.72%) were seropositive for HCMV IE1, CM2, p150, p65, gB1 and gB2 antigens, respectively. Concerning the band intensity of HCMV-IgM reactions with HCMV antigens, the rates of (+++) were higher than other band intensity for all antigens with highest rate for gB1 antigen (85.71%). So, the highest rate of HCMV-IgM reaction with the number of antigens was 40.90% for three antigens at the same time. In conclusion, the highest rate of HCMV-IgM in pregnant women was for gB1and p150 antigens; while the highest rate of intensity reaction was (+++)and the highest rate of HCMV-IgM ability for reaction was for three antigens at the same time.
The study aims at evaluating the relation of Candida spp. with diarrhea in children. A cross sectional study was carried out in Kirkuk city from 15th of January 2017 to 15th of June 2017. The number of patients under study were 120 children between 1 day to 12 years old. These patients admitted to Pediatric Hospital of Kirkuk. The control group who were matched to the patients studied, included 60 apparently healthy children and their ages were between 1 day to 12 years old. The study showed that the highest rate of Candida spp. was found in children with diarrhea comparing with the control (93.33% vs. 11.6%) with highly significant relation. In view of mixed infection of Candida spp., Table 2 shows that the highest rate of Candida spp. was C. albicans (26.57%) followed by 21.43% as C. tropicalis and the lowest rate was C. kafyr (6.25%) while the mixed infection by the four types recorded 30.36%. The highest rate of mixed Candida spp. infection with found in children who were infected with C. albicans with C. tropicalis (23.53%), followed by 17.65% with C. albicans and C. kyrosi (Table 3). Table 4 shows that the highest rates of Candida spp. found in patients who belonged to the age group 1-> 6 years (49.11%) while the lowest rates of Candida spp. infections occurred in age group 6-12 years. Candida spp. infection occurred more frequently in patients from rural areas than those from urban areas. It was concluded that Candida spp. was a highly related with diarrhea in children and Candida albicans was the most isolated species.
Background: Chronic kidney disease is one of the most common diseases. Health care workers in all countries of the world are concerned with the early detection and prevention of kidney diseases. Several novel diagnostic markers are being under investigation nowadays. Tumor necrosis factor-alpha and its receptors are examples.
Aim: The present study was conducted to evaluate the role of tumor necrosis factor α receptor 1 (TNFR1) as a biomarker for detection of renal dysfunction.
Materials and Methods: The study was carried out for the period from February to June 2019 and included 180 patients (their ages were between 19 and 85 years old) and were divided into 60 patients with renal impairment, 60 hemodialysis patients, and 60 patients with normal renal function (as a control group). Each group included patients with hypertension, patients with diabetes mellitus, and hypertensive- diabetic patients.
The patients were attended to Center of Kidney Disease and Transplantation, Dialysis Unit of Baghdad Teaching Hospital – Medical City , Dialysis Unit of Tikrit Teaching Hospital and private laboratory in Samarra City.
Urine sample was collected from each patient for bacteriological study and detection the level of TNFR1.
Results: The most common pathogen isolated from cultured samples was Escherichia coli. Concentration of urinary TNFR1 in hypertensive and or diabetic with normal kidney function compared with hypertensive or and diabetic renal impairment did not differ statistically significant. Conclusion: Urinary level of tumor necrosis factor receptor 1 (TNFR1) is not important in the diagnosis of renal impairment with the presence of hypertension and or diabetes mellitus. Through statistical comparisons of patients with urinary tract infection (UTI) group and those without UTI group , it seems that UTI does not affect the diagnostic ability of urinary TNFR1. We recommend future studies focusing on serum level of the receptors mentioned above to test their diagnostic potential in renal impairment. In addition, investigating the effect of the immunological causes of renal impairment on the level of TNFR, both in urine and serum.
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