In the course of studying the impact of metal compounds on the functioning of the endocrine system and adaptation systems in children living in chronic low-level multi-environmental (atmospheric air, drinking water) effects of a complex of metals, the elevated content of lead, manganese, nickel, cadmium and chromium was established to be 1.5 - 9.4 times higher than the reference level and 1.3 - 2.2 times than indices of the comparison group). In this contingent, disorders of the physical development and malnutrition (ICD: E44-46) were detected by 1.2 - 1.7 times more often than in conditions of sanitary and hygienic well-being. In the course of the analysis of the effectiveness of methods of correction in children of physical development disorders and malnutrition (E44-46) associated with the effects of metals, there was shown the high efficiency of the complex application of elimination, membrane stabilizing, antioxidant and nootropic technologies, with methods of physiotherapy (Ultrasound therapy, inductothermy) and exercise therapy. With comparable economic costs with traditional approaches, the proposed correction technologies demonstrate a significant benefit (up to 3.3 times) for the economy of the country and the region. The prevented losses for Gross Domestic Product (GDP) for the observation group are 13246.0 rubles per person per year (2.25 rubles per 1 ruble of costs, in contrast to 0.7 rubles when using standard methods).
Introduction. The modern educational process is characterized by an increase in the educational load, the use of teaching aids, which are not provided for in the regulatory and methodological documents. Violation of the hygienic principles of organizing the education of children at school is the basis for the development of somatic pathology. The aim of the study: hygienic assessment of the educational process in schools with various training programs. Materials and methods. The subject of the research is the organization of the educational process of the first, second and third levels of education in schools with in-depth study of the subjects of the physical and mathematical cycle (Secondary School of Physics and Mathematics) and a typical Secondary School. The questionnaire contained questions for the evaluation of the educational process on the factors “Complexity”, “Time”, “Additional load”. A comparative assessment of the compliance of the educational process in the secondary school of the FMC and the secondary school with the requirements of Sanitary Regulations and Norms (SanPiN) 2.4.2.2821-10 was carried out. Results. In secondary school of Physics and Mathematics, the intensity index of the load by the factor “Difficulty” was 1.8 times more and the ration of students with a high intensity of the educational process by the factor “Time” exceeded by 3 times if compared to the secondary school, and. Every fourth school student of specialized classes attended 2-3 additional education institutions. The shortage of training rooms reached 32%. Established violations in the organization of changes and breaks between shifts, load distribution during the week. The total weekly educational load at the first level of education exceeded the standard values by 20%. The total weekly workload during training at the second and third levels of education in secondary school Physics and Mathematics exceeded indices of secondary school by 1.3-1.4 times. Discussion. When introducing new specialized programs, the actual organization of the educational process does not meet sanitary requirements, which can lead to fatigue and the development of profound and lasting changes in the body of schoolchildren. Conclusion. In the school with in-depth study of subjects, the educational process is more intense. As part of the control and supervision activities in general education organizations of the innovative type, it is necessary to pay special attention to meeting the requirements of section X of Sanitary Regulations and Norms (SanPiN 2.4.2.2821-10).
The article presents the study results conducted to study the level and structure of children morbidity of preschool age living in the territories in zone of influence enterprises for metallurgical alumina production. We obtained data indicating the formation of residential areas where the multiplicity exceeding of MPCad on aluminum, formaldehyde, fluoride compounds, phenol, benzo (a) pyrene, suspended matter in atmospheric air is 1.16-43.6 times and on aluminum, nickel and manganese in drinking water is 1.25-42.2 times. We found that the content of chemical compounds (aluminum, manganese, chromium, nickel, phenol, formaldehyde, and ion fluoride) in the biological media of children of the observation groups was up to 4.2 times higher than those of the children of the comparison group. The morbidity of respiratory diseases, diseases of the blood, hematopoietic organs and disorders involving the immune mechanism, diseases of digestive, musculoskeletal and nervous systems in children living in the area of anthropogenic influences, up to 8.0 times higher than those of children living in the territory in the absence of enterprises influence. We proved the dependence of the registration frequency of the revealed pathology on the concentration in biomedia of chemicals (aluminum, copper, manganese, chromium, nickel, phenol, formaldehyde and ion fluoride), tropic to the organs of the respiratory, digestive, nervous and musculoskeletal systems.
High prevalence of allergic diseases among children and their close relation with quality of the environment require new approaches to organizing diagnostic and prevention activities. Our research objects were 247 children attending pre-school children facilities (PSCF). It was detected that children who permanently lived and/or attended a pre-school facility for not less than three years under long-term chemical aerogenic exposure to manganese and nickel compounds in low doses (0.17–0.23 MPC average daily) had contents of these metals in their blood that were 1.9–2.0 times higher than the same parameter in children from the reference group and 1.7–2.1 times higher than background level in the region. Pre-school children with their biological media being contaminated with nickel and manganese compounds suffered from atopic dermatitis, allergic rhinitis, and bronchial asthma 1.3–4.5 times more frequently (0.23R20.73; 59.2F388.1; р≤0.001). Allergic diseases associated with aerogenic exposure to chemicals with sensitizing power have certain pathogenetic peculiarities such as active overall inflammatory reaction; sensitization in 54–86% children (the parameter is 1.5–4.3 times higher than in the reference group); cellular metabolism disorder; depletion of antioxidant protection resources in 72% children; deficient activity of phagocytic and humoral section in immunity (1.2 times lower than in the reference group); cytokine regulation disorders (2.4–2.5 time difference); reduced expression of a receptor that induces activation apoptosis; stronger sympathetic influence on heart rate modulation in 26.0% children. Basing on statistical analysis and model making, we determined markers that showed occurring allergic reactions caused by aerogenic exposure to manganese and nickel compounds. These markers are targets for prevention activities; they include growth in allergic pathologies prevalence; these pathologies occurring together with chronic inflammatory-proliferative diseases and disorders in the vegetative nervous system; increased contents of leukocytes, eosinophils, and immunoglobulin E specific to nickel in blood; a decrease in phagocyte number and contents of IgM, IgА in blood serum (0.07≤R2≤0.74; 19.3≤F≤713.2; р≤0.0001).
Introduction. Osteopenic syndrome occupies one of the leading places among school-related pathology. Ultrasonic osteodensitometry is a non-invasive, low-cost method of early diagnosis of osteopenic conditions without specialized requirements. Material and methods. To identify the prevalence of osteopenic syndrome in schoolchildren, bone mineral density (BMD) was evaluated by ultrasound osteodensitometry. The study involved 84 boys and 85 girls aged from 7 to 17 years. Students were divided into six observation groups by gender and age. A survey of parents was carried out, and the social and economic characteristics of children’s lives were clarified. Given the presence or absence of signs of osteopenic syndrome according to the osteodensitometric study, a comparative assessment of the structure of concomitant pathology was carried out. Results. The prevalence of osteopenic syndrome among secondary schools students ranged from 28 to 65, depending on the students’ age and gender. In the junior schoolchildren, the proportion of boys with osteopenia was 2 times less than the proportion of girls (31.8 and 60%, p = 0.01). In the middle-grade students the frequency of osteopenia was comparable (65 and 53.3%, p = 0.2 ). Among high school students it was 2 times more common in young men (60 versus 28%, p = 0.02). In the structure of osteopenic syndrome, osteopenia of the first degree principally predominated. In children with ultrasonic signs of osteopenia, deforming dorsopathy was diagnosed 1.4 times more often (62 and 43.8%, p = 0.04), myopia - 2 times (26.2 and 13.5%, p = 0 04), functional dyspepsia - 1.6 times (42.4 against 25.8%, p = 0.02), a tendency to a more frequent prevalence of short stature (8.8 against 2.2%, p = 0, 06) and protein-energy deficiency (13.7 versus 5.6%, p = 0.07). Conclusion. The incidence of osteopenia among schoolchildren reaches 65%. The wider use of ultrasound osteodensitometry is necessary to timely determine BMD in students, given the non-specific manifestation of osteopenic syndrome.
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