Sanitary and hygienic analysis of drinking water quality was carried out and health risk assessment of
the population living in the industrial areas of the Perm region and consuming drinking water with
high content of organochlorine compounds (Tetrachloromethane to 3.7 MPC, chloroform to 2.8 MPC).
In the conditions of oral exposure to COC in the population formed unacceptable non-carcinogenic risk
of endocrine system pathology (HI = 1.72, due to the influence of chloroform (85.7 %). In exposed
children with high concentrations of chloroform and Tetrachloromethane in the blood, endocrine system
pathology was diagnosed 2,0–2,4 times more often, the relative risk of obesity (E66.0) and redundant
power supply (E67.8) 2.4 times higher than the indicators of the comparison group. A reliable causeand–
effect relationship between the development of metabolic disorders (obesity and overweight) and the
consumption of drinking water with high content of chos (OR = 2,4; DI = 1,05–6,8) was established; the
proportion of the explained variance was R2 = 0,3–0,34; 85,4 ≤ F ≥ 112,8; p < 0,001. As features of the
development of metabolic disorders in the population for a long time consuming drinking water with
high content of chos (Tetrachloromethane, chloroform) revealed a sharp disharmony of physical
development, early formation of excess body weight and obesity, an increase of 1,4–1,6 times the level Of
C-peptide and leptin in the blood, insulin resistance index HOMA-IR, (p < 0,05).
In the course of studying the impact of metal compounds on the functioning of the endocrine system and adaptation systems in children living in chronic low-level multi-environmental (atmospheric air, drinking water) effects of a complex of metals, the elevated content of lead, manganese, nickel, cadmium and chromium was established to be 1.5 - 9.4 times higher than the reference level and 1.3 - 2.2 times than indices of the comparison group). In this contingent, disorders of the physical development and malnutrition (ICD: E44-46) were detected by 1.2 - 1.7 times more often than in conditions of sanitary and hygienic well-being. In the course of the analysis of the effectiveness of methods of correction in children of physical development disorders and malnutrition (E44-46) associated with the effects of metals, there was shown the high efficiency of the complex application of elimination, membrane stabilizing, antioxidant and nootropic technologies, with methods of physiotherapy (Ultrasound therapy, inductothermy) and exercise therapy. With comparable economic costs with traditional approaches, the proposed correction technologies demonstrate a significant benefit (up to 3.3 times) for the economy of the country and the region. The prevented losses for Gross Domestic Product (GDP) for the observation group are 13246.0 rubles per person per year (2.25 rubles per 1 ruble of costs, in contrast to 0.7 rubles when using standard methods).
Evaluation of structural and dynamic indicators of the prevalence of endocrine diseases in adults and
children living in areas with different levels of exposure to chemical and range of environmental factors,
tropic to the endocrine system. Nosological entities identified priority to the worst dynamic trends (in
adults: diabetes (51,3 % in the pathology of endocrine structure) and thyroid disease (33,7 %) in
children - eating disorders (obesity and excess weight, 48,5 %), thyroid disease (46,1 %). In the complex
of sanitary-epidemiological criteria highlighted two types of areas in the Russian Federation with the
highest level of endocrine diseases (obesity and thyroid disease) and adverse sanitary situation.
According to the federal law «Formation of a system for motivating citizens to a healthy lifestyle, including healthy eating and giving up bad habits» (or «Strengthening public health») which is a part of «Demography» National project, there is a work needed for healthy food’s popularization including the development and realization of unique educational programs dedicated to rational and balanced nutrition. The aim of the investigation is a discussion of approaches to implementation target educational healthy nutrition programs. The scientific and educational centers of healthcare institutions and Federal Service for Supervision of Consumer Rights Protection and Human Welfare scientific organizations took part in developing the academic programs. Eight target programs were designed such as for preschool children, for pregnant and lactating women; for persons over working age; for persons with an increased level of physical activity; for the population working in hazardous and challenging working conditions; for people living in regions with specific environmental factors (micro-and macronutrients insufficiency, climate conditions). The development of interaction between particular departments of regional executive authority that take part in regional programs for implementing federal law «Strengthening public health» ministries or departments of the education and healthcare system is needed for reaching declared goals for the were educating the population on relevant knowledge and skills. The distribution of health nutrition educational program’s materials should be started among pupils in educational organizations considering the children’s physiologically determined learning ability. The projected difficulties can be the next: staff insufficiency in Federal Service for Supervision of Consumer Rights Protection and Human Welfare local authorities and organizations; lack of creativity during the choosing of using methods; the passivity of other ministries and departments; insufficient technical equipment in educational organizations; psychological resistance to innovations.
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