Microemulsions with a palm oil-based emollient, i.e., medium-chain triglyceride (MCT), and water or glycerol, stabilized by two oppositely charged ionic surfactants and a medium-chain alcohol, were investigated. The results showed that only the water-in-MCT or the glycerol-in-MCT microemulsions were prominent. The maximum solubilization of the MCT emollient was higher in cetyftrimethyI ammonium bromide, i.e., the positively charged surfactant that contained a nitrogen atom, than the negatively charged surfactant sodium dodecyl sulfate. However, the results did not lend themselves for select, ing any decisive factor that would explain the different solubilization behavior encountered in the investigated aqueous and nonaqueous systems. JAOCS 72, 151-155 (1995). KEY WORDS: Cetyltrimethylammonium bromide, MCT emollient, microemulsion, palm oil, sodium dodecyl sulfate, solubility.
A model for the structure of the stratum corneum lipids was analyzed using small angle x-ray diffractometry and optical microscopy.The small angle X-ray diffractograms showed the lipids to be partitioned in the hydrated acid/soap host layered structure between the methyl group layers. The exception is cholesterol which was entirely located in the acid/soap chains and which, in addition, attracted other compounds from the location between the methyl group layers.
371Copyright@ 1988 by Marcel Dekker, Inc.
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