The effect of low exposure doses of gamma ray at doses of 0.055 Gy, 0.11 Gy and 0.165 Gy on the some hematological parameters of albino female rats were investigated. At the end of exposure periods and Blood samples were collected for analyses. The results obtained when increases of gamma ray doses of rats caused significant, p ≤ 0.05, decrease in the RBCs, Hb and Ht%. Also it was found elevation in MCV and MCH with increased exposure dose as well as significant decreases, p≤ 0.05, Platelets in decreasing with increasing of doses rate and while MCHC% did not change significantly. But it was found when increases of gamma ray doses of rats caused significant, p ≤ 0.05, decrease in WBCs count, lymphocytes count, monocytic, neutrophils, esinophiles and basophiles respective controls. These findings on the some hematological parameters suggest that the changes in blood parameters of the treated rats were due to the exposure of low doses of gamma ray.

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The integumentary system covers the surface of the embryo (skin) and its specialized skin structures including hair, nails, sweat glands, mammary glands and teeth. During fetal skin development, the epidermis changes from a single layer of ectodermal cells at 7–8 days of gestation into a more apparent stratified, keratinized epithelium at 22–24 weeks. The aim of the study is to identify the histological and cytological changes that take place during neonatal and adult epidermis development. Human neonatal and adult samples were obtained from fully informed, consenting parent or releatives from Al-hilla mortary / Iraq. Neonatal samples were obtained from neonates after sudden deaths from maternity wards. Anatomical Sites included abdomen, forehead, back, shoulder and feet sole. A totoal of 15 neonates and 10 mature adults were used for this study. Fresh tissues were sectioned using a freezing cryostat. Tissues were sectioned at 5µm in -24°C and collected on microscopic slides. Slides were allowed to air dry for 30 min prior to hematoxyline and eosin staining. Tissues were also photographed using scanning electron microscopy SEM. Cytological measurements were taken using image j software and data was analysed using graph prism. Various cytological and histological changes takes place during neonatal and adult and epidermis development. Our study shows the stages of fair follicule formation as well as number of nucleated layers present at each stage of development and at different anatomical sites. Major histological changes takes places during the transition frm a neonate to a mature adult including the number of basal cells and epidermal thickness depending on the anatomical site.

The kidneys are major organs that clear the drugs. Urine is one of the primary elimination routes for drugs and metabolites to be excreted outside of the body. Most drugs are predominantly excreted via the kidneys as their metabolized products. The histopathological change of kidney in the rats that treated with indomethacin at dose (20mg/kg)show abnormal structure of glomerulus is more damage and bowmanand#39;s space is very swelling ,distortion glomerulus and the compound inside it is shrinkage with presence of inflammation cell and bleeding fibrosis, when compared with control. While the change of kidney in the rats that treated with indomethacin at dose (50mg/kg) Showed abnormal structure of glomerulus is shrinkage with tubular cellular swelling and necrosis and presence of interstitial inflammation and swelling tubular. when used hesperidin show protective effect of antioxidant normal structure of glomerulus and renal tubule also no necrosis or swelling ,the Bowman’s space and capsule is normal.