Background: Acute gastroenteritis stemming from viral causes is very common during the childhood period. Rotavirus and enteric adenovirus are the most common factors of acute gastroenteritis encountered in infants and children. However, the epidemiology of rotavirus and enteric adenovirus gastroenteritis in the east Anatolia region is not well-known. Objectives: We aimed to evaluate the relationship between the distribution of antigen positivity in rotavirus and enteric adenovirus antigen tests required cases and demographic data retrospectively in pediatric patients admitted to our hospital. Patients and Methods:The records of stool sample analyses for 1154 patients admitted to our hospital from June 2011 to December 2011 with complaints of diarrhea were retrospectively examined. The presence of rotavirus and enteric adenovirus antigens in stool specimens was investigated by means of an immunochromatographic test. Results: Viral antigens were detected in 327 (28.3%) stool specimens out of 1154. Among the positive results, the frequency was 73.7% for rotavirus and 26.2% for adenovirus. While the detected rotavirus antigen rate was high for all age groups, it was highest for children under the age of 2, with a rate of 57.1%. Moreover, the rotavirus infections were observed at a rate of 44.3% in winter and of 24.6% in autumn. Conclusions:The most important factor in childhood acute gastroenteritis in east Anatolia is the rotavirus. Rotavirus and adenovirus antigens should be routinely investigated as a factor in fresh stool samples for the accurate diagnosis and treatment of gastroenteritis in children in the winter and autumn months.
Brucellosis is a zoonotic disease of worldwide and still remains endemic in some developing countries, especially in Turkey. Milk is the main food product serving as a vector for Brucella. In this study we aimed to investigate the seroprevalence of human and animal brucellosis. The study group consisted of 358 subjects who had high risk occupations of animal breeder and farmer. The test results were interpreted and titers equal or in excess of 1/40 were considered significant. 189 farm animals were incorporated to our research. Among these animals, 104 of them were sheep and goat and 85 of them were cattle. The Brucellosis Milk Ring Test was used to test raw milk samples collected the selected herds in the study area. The seroprevalence of human brucellosis was 6.7%. Seroprevalence of animal brucellosis was found as 22.75% in livestocks. This study is important for being the first study in recent years that demonstrates the Brucella seropositivity rates in Igdır Province. This high seropositivity in our region may depend on the high rates of animal brucellosis; those of which were inadequate under control by veterinary and by vaccination and people who consume the milk by without boiling.
Background: Burn wound is an important health problem worldwide. Serious outcomes related with burn occur and treatments focus on healing of the wounded area with dermal preparations containing chemicals avoiding growth of pathogenic organisms. Plants are important sources for both modern pharmacy to find new molecules used in modern medication as well as in traditional medicinal practices. Many plants are used for treatment of burn wounds. Asphodel (Asphodelus aestivus Brot.) is a naturally found plant in the Mediterranean flora. It is also used in traditional medicinal practices in Turkey. Aim: In this study it was aimed to test wound healing effect of Asphodel. Materials and Methods: An ointment prepared with a 5% methanolic extract of Asphodel was used. 4 groups were formed as control, wound, wound+asphodel and wound+standard drug (oxytetracyclin hydrochloride) (n=8 in each group). Burn wound was established with a thermal induction. Biochemical, microbiological and histopathological evaluations were performed. Results: Biochemical results (Alt, Ast, Glucose, Ldh) obtained from blood samples showed no adverse effect of this administration. Microbiological results showed a protective effect of Asphodel similar with standard drug. Histopathological evaluation also presented an ameliorating effect as standard drug. Conclusion: Results of this study states that traditional use of this plant for the treatment of burn/wound/ulcer in traditional medicine applications is valid.
Infectious diseases have been one of the most important problems affecting all societies since the existence of mankind. Streptococci, one of the causes of these diseases, can be found in the normal flora of the mouth, nose, throat, skin, digestion and genital system in humans. Streptococci are an important cause of diseases in humans such as meningitis, acute otitis media, rhinosinusitis and community-acquired pneumonia. In this study, various clinical samples belonging to the disease were taken between January and Septe mber 2015. All necessary permission documents and the ethics committee approval numbered 2 and dated 13.11.2014 for clinical investigations were obtained. The collected samples were brought to the Microbiology Laboratory of Van Yüzüncü Yıl University Medical Faculty. Analyzes of determined and identified antibiotic resistance genes of isolated and identified streptococci strains were carried out in the Microbiology laboratory of Yüzüncü Yıl University Faculty of Pharmacy by PCR. The detection of pbp1a for penicillin G antibiotic, pbp2x for cefotaxime antibiotic, and gyrA resistance genes for quinolone antibiotics were targeted. In this study, the primers used in Table-2 were taken as reference. A total of 30 streptococcus strains were isolated and identified from various clinical samples including 8 sputum, 6 urine, 5 BOS, 4 blood, 4 nasopharyngeal swab, 2 ear effusion and 1 ab scess. As a result of the PCR analysis, the resistance of pbp1a was found in 6 of the streptococcal isolates, pbp2x in 8, and resistan ce in the gyrA gene region in 5. In our study, no three resistance genes were found in 22 isolates and the presence of all three (pbp1a, pbp2x and gyrA) resistance genes in 5 isolates was determined. It is expected that the data obtained from this research will contribute to national and international knowledge accumulation.
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