The Prevalence of Rotavirus and Adenovirus in the Childhood Gastroenteritis

Abstract

Background: Acute gastroenteritis stemming from viral causes is very common during the childhood period. Rotavirus and enteric adenovirus are the most common factors of acute gastroenteritis encountered in infants and children. However, the epidemiology of rotavirus and enteric adenovirus gastroenteritis in the east Anatolia region is not well-known. Objectives: We aimed to evaluate the relationship between the distribution of antigen positivity in rotavirus and enteric adenovirus antigen tests required cases and demographic data retrospectively in pediatric patients admitted to our hospital. Patients and Methods:The records of stool sample analyses for 1154 patients admitted to our hospital from June 2011 to December 2011 with complaints of diarrhea were retrospectively examined. The presence of rotavirus and enteric adenovirus antigens in stool specimens was investigated by means of an immunochromatographic test. Results: Viral antigens were detected in 327 (28.3%) stool specimens out of 1154. Among the positive results, the frequency was 73.7% for rotavirus and 26.2% for adenovirus. While the detected rotavirus antigen rate was high for all age groups, it was highest for children under the age of 2, with a rate of 57.1%. Moreover, the rotavirus infections were observed at a rate of 44.3% in winter and of 24.6% in autumn. Conclusions:The most important factor in childhood acute gastroenteritis in east Anatolia is the rotavirus. Rotavirus and adenovirus antigens should be routinely investigated as a factor in fresh stool samples for the accurate diagnosis and treatment of gastroenteritis in children in the winter and autumn months.

Prevalence and diversity of rotavirus A genotypes cirulating in Turkey during a 2‐year sentinel surveillance period, 2014‐2016

“…In Turkey, acute gastroenteritis is a serious public health problem, affecting over 352 000 children younger than 5 years old annually (http://tsim.saglik.gov.tr/tsim). Recent studies have revealed that RVA is responsible for 6‐28% of cases of childhood gastroenteritis . Rotavirus infections in Turkey are most commonly observed between the beginning of September and the end of May, with the highest rates occurring in the first 4 months of the year .…”

“…Recent studies have revealed that RVA is responsible for 6-28% of cases of childhood gastroenteritis. [24][25][26][27][28] Rotavirus infections in Turkey are most commonly observed between the beginning of September and the end of May, with the highest rates occurring in the first 4 months of the year. 9 More than one third of infections occur in children younger than 2 years of age, 9,24 and rates of rotavirus positivity are similar between males and females.…”

“…[24][25][26][27][28] Rotavirus infections in Turkey are most commonly observed between the beginning of September and the end of May, with the highest rates occurring in the first 4 months of the year. 9 More than one third of infections occur in children younger than 2 years of age, 9,24 and rates of rotavirus positivity are similar between males and females. 9 Genotyping studies from different provinces over various time periods have indicated that G1-G4 and G9 are the five most common genotypes and that there is major variation in the frequency of each of these genotypes over time.…”

Prevalence of Cyclospora cayetanensis and other enteropathogen among children under the age of 15 years in Biratnagar, Nepal

“…The high prevalent rate of rotavirus found in this study under 5 years of age may be due to underdeveloped immune system of children, lack of hygienic practices and consumption of raw food and untreated water. In several literatures, rotavirus is considered as the most common cause of viral gastroenteritis [7,8].…”

“…play a vital role in causing diarrhoea [5,6]. Rotavirus remains the most common cause of severe diarrhoea and adenovirus causes acute gastroenteritis under the age of 5 years [7,8]. Three forms of diarrhoea (watery diarrhoea, bloody diarrhoea and persistent diarrhoea) are potentially lifethreatening diarrhoea during childhood.…”