Background: Binahong (Anredera cordifolia (Ten.) STEENIS) is a widely available herbal plant in Indonesia and has been intensely researched for its healing abilities due to its biological activities, but few have studied its capability in accelerating hard tissue healing in post-extraction tooth sockets. The purpose of this study was to analyse the effects of 3% binahong leaf extract gel on alveolar bone healing in post-extraction sockets in Wistar rats. Methods: In this study, 48 male Wistar rats were randomly allocated to twelve groups. After the extraction of the left mandibular incisor, sockets in Group I to IV were given 3% binahong leaf extract gel, group V to VIII were given a control gel, and group IX to XII were given Gengigel® for 14 days. The residual socket volume (RSV) and fibroblast proliferation were observed on the 3rd, 7th, and 14th day post-extraction, while the osteoblast and osteocyte proliferation were observed on the 7th, 14th, and 28th day post-extraction. The RSV data were analysed using repeated measure ANOVA and one-way ANOVA, while the histopathological data were analysed using one-way ANOVA. Results: The results showed that the binahong group had the lowest RSV and the highest fibroblast proliferation compared to the other groups on the 7th day (p<0.05) and the highest osteoblast and osteocyte proliferation compared to the other groups on the 14th day (p<0.05). Conclusion: The experiment showed that 3% binahong leaf extract gel could accelerate wound closure, which was characterized by a greater decrease in the RSV value in comparison to the other treatment groups and could enhance alveolar bone healing by increasing the proliferation of fibroblasts, osteoblasts, and osteocytes.
Background: Binahong (Anredera cordifolia (Ten.) STEENIS) is a widely available herbal plant in Indonesia and has been intensely researched for its healing abilities due to its biological activities, but few have studied its capability in accelerating hard tissue healing in post-extraction tooth sockets. The purpose of this study was to analyse the effects of 3% binahong leaf extract gel on alveolar bone healing in post-extraction sockets in Wistar rats. Methods: In this study, 48 male Wistar rats were randomly allocated to twelve groups. After the extraction of the left mandibular incisor, sockets in Group I to IV were given 3% binahong leaf extract gel, group V to VIII were given a control gel, and group IX to XII were given Gengigel® for 14 days. The residual socket volume (RSV) and fibroblast proliferation were observed on the 3rd, 7th, and 14th day post-extraction, while the osteoblast and osteocyte proliferation were observed on the 7th, 14th, and 28th day post-extraction. The RSV data were analysed using repeated measure ANOVA and one-way ANOVA, while the histopathological data were analysed using one-way ANOVA. Results: The results showed that the binahong group had the lowest RSV and the highest fibroblast proliferation compared to the other groups on the 7th day (p<0.05) and the highest osteoblast and osteocyte proliferation compared to the other groups on the 14th day (p<0.05). Conclusion: The experiment showed that 3% binahong leaf extract gel could accelerate wound closure, which was characterized by a greater decrease in the RSV value in comparison to the other treatment groups and could enhance alveolar bone healing by increasing the proliferation of fibroblasts, osteoblasts, and osteocytes.
Objective: This research was conducted to determine the effectiveness of binahong (anredera cordifolia (ten.) steenis) leaves extract in inhibiting the streptococcus mutans growth. Material and Methods:The study is true experimental laboratories with posttest-only control group design. The study sample used was Binahong leaves and streptococus mutans bacteria that were multiplied in Microbiology Laboratory of the Faculty of Pharmacy, Universitas Sumatera Utara. This study used seven treatment groups namely, 75%, 50%, 25%, 12.5%, 6.25% Binahong leaf extract, amoxicillin (positive control) and Dimethyl Sulfoxide (DMSO) (negative control). Testing the treatment group for the Streptococcus mutans was carried out using the Kirby-Bauer disk diffusion method with four repetitions. Extract was done by maceration using 96% ethanol solvent.Results: Indicate that the binahong leaves (anredera cordifolia (ten.) steenis) extract can inhibit the growth of streptococcus mutans which can be seen from the clear zone formed on paper discs that have been given binahong leaves extract with a concentration of 75%, 50%, 25%, 12, 5%, 6.25%, along with amoxicillin and dimethylsulfoxide/DMSO. The results also showed a significant difference in diameter of the inhibition zone from each treatment group (p <0.005). Conclusion: Binahong (anredera cordifolia (ten.) steenis) leaf extract has antibacterial ability because it can inhibit the growth of Streptococcus mutans in the oral cavity and compared to other concentrations, 75% concentration is more effective in inhibiting the growth of streptococcus mutans in the oral cavity.
Pendahuluan: Pencabutan gigi merupakan prosedur yang sering dilakukan di kedokteran gigi. Setelah pencabutan gigi akan dihasilkan suatu perlukaan. Proses penyembuhan luka dapat dipercepat pada kondisi tertentu. Salah satu bahan alami yang dapat membantu proses penyembuhan luka adalah getah tanaman betadine (Jatropha multifida L.). Penelitian bertujuan untuk menganalisis efektivitas getah tanaman betadine terhadap penyembuhan luka dan terhadap tanda-tanda infeksi pasca pencabutan gigi Metode: Desain penelitian studi eksperimental laboratorium dengan rancangan penelitian post-test only control group design menggunakan 30 ekor tikus Sprague-Dawley. Teknik pengambilan sampel yaitu convenience sampling. Sampel dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan getah tanaman betadine dan kelompok kontrol diberikan asam traneksamat secara oral menggunakan sonde lambung. Tunggu selama 4 jam setelah pemberian getah tanaman betadine dan asam traneksamat. Anestesi pada tikus menggunakan ketamin 50 mg/kg berat badan secara intramuskular kemudian dilakukan pencabutan pada gigi tikus. Pengamatan dilakukan dengan melihat kriteria klinis pada hari 1,3,7 dan diperhatikan sampai luka sembuh serta lihat tanda-tanda infeksi. Analisis data dilakukan dengan uji normalitasShapiro Wilik. Hasil penelitian menunjukkan bahwa data berdistribusi tidak normal. Analisis data dilanjutkan menggunakan uji statistik mann whitney. Hasil: Terdapat perbedaan signifikan penyembuhan luka soket pasca pencabutan gigi setelah diberikan getah betadine dan asam traneksamat dengan nilai p=0,037 (p<0,005). Simpulan: Pemberian getah tanaman betadine terbukti lebih efektif terhadap proses penyembuhan luka soket pasca pencabutan gigi dibandingkan dengan pemberian asam traneksamat. Kata kunci: tikus Sprague-Dawley; penyembuhan luka; pencabutan gigi; getah batang betadine ABSTRACTIntroduction: Tooth extraction is a procedure often performed in dentistry. Tooth extraction will always cause injuries. However, the wound healing process can be accelerated under certain conditions. One of the natural ingredients that can accelerate the wound healing process is betadine (Jatropha multifida L.) plant sap. The study was aimed to analyzed the effect of betadine plant sap on wound healing and signs of infection after tooth extraction. Methods: Experimental laboratory study design with post-test only control group design was conducted towards 30 Sprague-Dawley rats. The sampling technique was convenience sampling. The sample was divided into two groups, the treatment group and the control group. The treatment group was administered with betadine plant sap, and the control group was administered with tranexamic acid orally using a gastric probe, then waited 4 hours after. The anaesthesia was then performed using 50 mg/kg body weight of ketamine intramuscularly. The extraction was performed after. Observations was conducted at the clinical criteria on days 1, 3, and 7 and continue to be monitored until the wound heals. Then, the signs of infection were observed. Data analysis was carried out using the Shapiro Wilk normality test. The results showed that the data was not normally distributed. Thus, data analysis was continued using the Mann Whitney statistical test. Results: The results showed a significant difference in the healing of socket wounds after tooth extraction after being administered with betadine sap and tranexamic acid with a value of p=0.037 (p<0.005). Conclusions: Administration of betadine plant sap is proven to be more effective in accelerating the healing process of socket wounds after tooth extraction than tranexamic acid. Keywords: Sprague-Dawley rats; wound healing; pencabutan gigi; getah batang betadine
The inferior alveolar nerve block technique (Fischer's method) is a local anesthetic technique that is often used in daily dental and surgical treatment. However, the failure rate reaches 15-20% because many factors affect the technique's success. Therefore, this descriptive study aims to determine the knowledge of clinical dental students regarding the inferior alveolar nerve block technique and the management of the failure associated with its characteristics. A cross-sectional approach was employed by using a validated questionnaire consisting of 2 parts, namely 6 general questions and 12 knowledge questions, which were distributed to 68 clinical dental students in the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Universitas Sumatera Utara in 2019. The results showed that 51.5% of the students had good knowledge, 41.2% had fair knowledge and 7.4% had less knowledge. The highest percentage of students based on male gender had fair knowledge (10 people out of 15) and the female had good knowledge (30 people out of 53). The clinical dental students’ level of knowledge based on whether they have ever or never failed to perform an anesthetic block technique is in a good category. In conclusion, most of the clinical dental students at the Department of Oral Surgery in 2019 had a good level of knowledge about the inferior alveolar nerve block technique and its failure management.
Karsinoma sel skuamosa rongga mulut (KSSRM) merupakan neoplasma ganas epitelial yang menunjukkan diferensiasi sel skuamosa ditandai dengan adanya pembentukan keratin. Insidensi kanker mulut masih terus meningkat dan hampir semua penderita kanker mulut ditemukan ketika sudah berada pada stadium lanjut. Salah satu faktor yang dapat menimbulkan keterlambatan diagnosis ini adalah dokter gigi yang kurang teliti dalam pemeriksaan rutin rongga mulut atau tidak memiliki pengetahuan yang cukup mengenai keganasan di rongga mulut. Deteksi dini kanker mulut menjaga kelangsungan hidup pasien dan prognosis menjadi lebih baik. Tujuan penelitian mengetahui tingkat pengetahuan dokter gigi mengenai deteksi dini dan diagnosis karsinoma sel skuamosa rongga mulut. Metode: Jenis penelitian menggunakan teknik purposive sampling dengan menggunakan kuesioner online kepada 106 dokter gigi di Kota Medan. Responden dipilih dengan yaitu responden yang diteliti berdasarkan kriteria yang telah ditentukan. Analisis data yang digunakan disribusi frekuensi. Hasil: Sebanyak 56,6% responden memiliki tingkat pengetahuan baik, 41,1% responden memiliki tingkat pengetahuan yang cukup dan 2,7% responden memiliki tingkat pengetahuan kurang/rendah. Simpulan: Pengetahuan dokter gigi mengenai deteksi dini dan diagnosis KSSRM termasuk dalam kategori baik, namun terdapat beberapa responden yang memiliki pengetahuan cukup hingga kurang. Kata kunci: OSCC; deteksi dini; pengetahuan; dokter gigi Knowledge level of dentists about early detection and diagnosis of oral squamous cell carcinoma
Dental caries is a disease that is mostly found in the oral cavity together with periodontal disease, so it is a major problem of dental and oral health. Based on the results of basic health research (RISKESDAS) in 2007 in 28 Indonesian provinces, it was found that the prevalence of caries in Indonesia was 67.4%, while the prevalence of active caries (untreated caries) was 43.4%. Many children have cavities and residual roots. Children are not able to independently maintain the health of their teeth and mouth. Apart from parents, school teachers have a big role in improving children's oral and dental health. The role of the teacher is meaningful in this case, because the teacher will meet almost every day with the child. However, the reality is that school teachers do not have skills in maintaining oral health, and the level of knowledge about oral health is still low. Therefore, community service for children is needed in the form of dental health education and joint tooth brushes. Besides that, skills training on brushing teeth also needs to be carried out for teachers. The aim of this service is to improve children's dental health by providing dental health education, joint brushing and increasing teacher knowledge and skills in helping to brush teeth in school children. The method of implementing community service is in the form of dental health education for children, and conducting training for school teachers on oral and dental health. It is hoped that with the dedication carried out, there will be an increase in dental and oral health in children and an increase in knowledge and skills of school teachers.
Objective: This study aims to determine the effectiveness of lidocaine of local anaesthetic agent in inhibiting the growth of streptococcus mutans bacteria. Material and Methods: This type of research is a laboratory experimental with a post test only control group design. Microorganism used was streptococcus mutans and cultured at the Microbiology Laboratory of the Pharmacy, Universitas Sumatera Utara. The local anaesthetic tested was a solution of lidocaine diluted with NaCl 0.9% to 0.5%, 1%, and 2%. The antibacterial activity test was carried out using diffusion method by dripping 25 µl of lidocaine (0.5%, 1%, 2%), positive control (amoxicillin), and negative control (NaCl 0.9%) on disc paper, then placed on nutrient agar, and incubated. After 24 hours, the inhibition zone formed around the disc paper was observed. Results: Lidocaine showed antibacterial activity with the inhibition zone of 0.5%, 1%, 2% concentration was 6.98 mm, 7.66 mm, 8.36 mm. Then the data was analyzed using the One-way ANOVA test. From these results, there was a significant difference in the mean of the inhibitin zone (p < 0.05) between 0.5%, 1%, and 2% lidocaine, positive control, and negative control. Conclusion: Lidocaine has antibacterial activity against Streptococcus mutans bacteria with an effective concentration of 2%.
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