Objective: To compare post-odontectomy wound healing time using silk and catgut sutures at Pirngadi Hospital from May to June 2018. Material and Methods: This is anon-laboratory experimental study with a "post-test only"design. Wound healing scores was assessed on the first and seventh days post odotectomy by seeing signs of inflammation. The number of patients studied was 30 people which 15 people used silk and 15 people used catgut. Results: The results were statistically analyzed using Mann-Whitney Test. There was no significant relationship (p> 0.05) between the wound healing time to the suture type on the first day post odontectomy. On the seventh day, it was found that there was a significant relationship (p <0.05) which silk had a score of 1.40 ± 0.507 while catgut had a score of 1.07 ± 0.258. Conclusion: Catgut has a better wound healing time than silk.

Material and Methods: This is an experimental study with pre-test pos-ttest group design carried out by purposive sampling technique. In this study, sample were divided into 2 groups and each consist of 20 people which are handrubbing and handwashing groups. Bacterial samples were obtained by placing the right hand in a container that contain NaCl 0.9% solution for 1 minute. Samples were then grown in nutrient agar plate and incubated at 37°C for 48 hours. The culture results were calculated using the colony counter tool. Results: There is a significant difference before and after handrubbing with significance 0.00 (P<0.05) and before and after handwashing with significance 0.001 (p<0.05) in reducing bacterial colonization in hand with. However, there is no significant association between handrubbing and handwashing method in reducing the number of bacterial colonization with a significance number of 0.892 (p> 0.05). Conclusion: There is no significant differences between handrubbing and handwashing in reducing the number of bacterial colonization.

Objective: To determine the effectiveness of using green betel leaf (Piper bettle Linn) extract hand sanitizer gel in reducing the number of bacterial colonies in the palms of hand. Method: In this experimental research with posttest only with control group de-sign using dental clinical clerkship students of Faculty of Dentistry Universitas Sumatera Utara. They were evenly divided into 5 groups. They were chlorhexidine gel (group 1), 1% green betel leaf extract (group 2), 3% green betel leaf extract (group 3), 5% green betel leaf extract (group 4), and use of placebo (group 5). Bacterial colonies isolated from the swabs were identified by stan-dard microbiological procedures. All statistical analysis methods were conducted using the one-way Anova and posthoc LSD tests. Results: The results of univariate analysis showed that sig <0.05, meaning that there was a difference in the number of bac-terial colonies between chlorhexidine, 1%, 3%, and 5% green betel extract gel. The one-way Anova test at 95% confidence level proved that the differences are significant at p-value 0,001. Conclusion: There is a difference in the effectiveness of using a hand sanitizer for green betel leaf extract on the number of bacterial colonies in the palms of hand. Hand sanitizer green betel leaf extract gel 5% more effective than 1% and 3% concentrations.

Objective: This study aims to investigate the effects of black cumin extract (Nigella sativa) on the process of wound healing in tooth extraction sockets. Material and Methods: This study involved 24 patients from the Department of Oral and Maxillofacial Surgery grouped into the control and treatment groups. After extracting the first or second molar left or right in adult patients, the black cumin extractwas applied to the socket in the treatment group as soon as possible while it was not applied in the control group. The sockets were divided into 1,2,3 groups, which were treated as black cumin extracts of 10%, 12%, and 14% respectively. On day 1,3,7, patients were recalled and sockets size were calculated to analyze wound healing. Results: Black cumin was found to be able to make the wound healing faster in the treatment group when compared to the control group. Although the effect was not immediately apparent on the second day, on the seventh day the group treated with black cumin extract had a smaller sizing average compared to the control group. The concentration of 12% black cumin extract was found to have the best effect on wound healing. Significance of findings: Black cumin extract can make wound healing in tooth extraction sockets in patients.

Pendahuluan: Pencabutan gigi merupakan prosedur yang sering dilakukan di kedokteran gigi. Setelah pencabutan gigi akan dihasilkan suatu perlukaan. Proses penyembuhan luka dapat dipercepat pada kondisi tertentu. Salah satu bahan alami yang dapat membantu proses penyembuhan luka adalah getah tanaman betadine (Jatropha multifida L.). Penelitian bertujuan untuk menganalisis efektivitas getah tanaman betadine terhadap penyembuhan luka dan terhadap tanda-tanda infeksi pasca pencabutan gigi Metode: Desain penelitian studi eksperimental laboratorium dengan rancangan penelitian post-test only control group design menggunakan 30 ekor tikus Sprague-Dawley. Teknik pengambilan sampel yaitu convenience sampling. Sampel dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan getah tanaman betadine dan kelompok kontrol diberikan asam traneksamat secara oral menggunakan sonde lambung. Tunggu selama 4 jam setelah pemberian getah tanaman betadine dan asam traneksamat. Anestesi pada tikus menggunakan ketamin 50 mg/kg berat badan secara intramuskular kemudian dilakukan pencabutan pada gigi tikus. Pengamatan dilakukan dengan melihat kriteria klinis pada hari 1,3,7 dan diperhatikan sampai luka sembuh serta lihat tanda-tanda infeksi. Analisis data dilakukan dengan uji normalitasShapiro Wilik. Hasil penelitian menunjukkan bahwa data berdistribusi tidak normal. Analisis data dilanjutkan menggunakan uji statistik mann whitney. Hasil: Terdapat perbedaan signifikan penyembuhan luka soket pasca pencabutan gigi setelah diberikan getah betadine dan asam traneksamat dengan nilai p=0,037 (p<0,005). Simpulan: Pemberian getah tanaman betadine terbukti lebih efektif terhadap proses penyembuhan luka soket pasca pencabutan gigi dibandingkan dengan pemberian asam traneksamat. Kata kunci: tikus Sprague-Dawley; penyembuhan luka; pencabutan gigi; getah batang betadine ABSTRACTIntroduction: Tooth extraction is a procedure often performed in dentistry. Tooth extraction will always cause injuries. However, the wound healing process can be accelerated under certain conditions. One of the natural ingredients that can accelerate the wound healing process is betadine (Jatropha multifida L.) plant sap. The study was aimed to analyzed the effect of betadine plant sap on wound healing and signs of infection after tooth extraction. Methods: Experimental laboratory study design with post-test only control group design was conducted towards 30 Sprague-Dawley rats. The sampling technique was convenience sampling. The sample was divided into two groups, the treatment group and the control group. The treatment group was administered with betadine plant sap, and the control group was administered with tranexamic acid orally using a gastric probe, then waited 4 hours after. The anaesthesia was then performed using 50 mg/kg body weight of ketamine intramuscularly. The extraction was performed after. Observations was conducted at the clinical criteria on days 1, 3, and 7 and continue to be monitored until the wound heals. Then, the signs of infection were observed. Data analysis was carried out using the Shapiro Wilk normality test. The results showed that the data was not normally distributed. Thus, data analysis was continued using the Mann Whitney statistical test. Results: The results showed a significant difference in the healing of socket wounds after tooth extraction after being administered with betadine sap and tranexamic acid with a value of p=0.037 (p<0.005). Conclusions: Administration of betadine plant sap is proven to be more effective in accelerating the healing process of socket wounds after tooth extraction than tranexamic acid. Keywords: Sprague-Dawley rats; wound healing; pencabutan gigi; getah batang betadine

BACKGROUND: Pugun Tanoh (Curanga fel-terrae (Lour.) Merr) is one of the medicinal plants. C. fel-terrae often used by the Karo tribe of Tiga Lingga Village, Kabupaten Dairi, Provinsi Sumatera Utara to treat diarrhea, asthma, cough, scabies, inflammation, bruising, and abdominal pain. Hence, it is necessary to examine the anti-inflammatory effects of Pugun Tanoh leaf extract. AIM: The present study aimed to determine the effectiveness of Pugun Tanoh leaves ethanol extract as an anti-inflammatory in patients after tooth extraction at Dental and Mouth Hospital of Dentistry Faculty, Universitas Sumatera Utara. METHODS: There were two research groups, namely the treatment group, which was given the extract plus amoxicillin 500 mg and mefenamic acid 500 mg as well as the control group who were only given amoxicillin 500 mg and mefenamic acid 500 mg without the extract. However, the instructions given to the patient are only required to take 500 mg of amoxicillin as an antibiotic, but for the 500 mg mefenamic acid drug, it is only instructed to drink it if there is pain that is felt by the patient. After the extracted teeth, the treatment group was given C. fel-terrae leaves ethanol extract 1.1 mg/kg on the tooth extraction socket using a 3 ml syringe then measurements were made on day 1 and day 2 after the extract was given using a visual analog scale (VAS) and through direct observation. Statistical analysis using the t-test independent and Chi-square test (significant p < 0.05). RESULTS: The treatment group did not have signs of inflammation both on the 1st and 2nd days after tooth extraction, while the control group had signs of inflammation both on the 1st day and the 2nd day after tooth extraction. In the treatment group, there were no patients who took the mefenamic acid drug while in the control group, it was found that all patients took mefenamic acid because they felt post-extraction pain. Statistical result are obtained with p = 0.00 (p < 0.05). CONCLUSION: C. fel-terrae leaves ethanol extract is effective to be used as an anti-inflammatory in patients after tooth extraction combined with amoxicillin 500 mg and mefenamic acid 500 mg.

Objective: Tooth extraction in oral surgery can lead to bleeding. Ozone water is a material that is able to accelerate healing process and prevent socket inflammation by stimulating and speeding up the work of cells like fibroblasts. Moreover, ozone water quickens the release of oxygen to the tissue to kill microorganism in tooth socket and accelerate healing process. Material and Methods: This is experimental research using post-test only with control group design. Ozone water is made using DSM Aero High Voltage. The ozonation process takes 30 minutes and followed by soaking a tampon in the ozone water. Patients in the treatment group bite the tampon for 30 minutes while patients in the control group bite a dry tampon. After 30 minutes, the tooth socket is checked to observe the inflammation using the Gingival Score Index. Patients are instructed to come back 7 days after the tooth extraction to check on the inflammation. There is a total of 38 samples in the study and they are divided into 2 groups (treatment and control). This study is conducted in the Department of Oral Surgery and Maxillofacial Faculty of Dentistry USU. Results: The average of Gingival Index after 30 minutes is 0.42±0.507 and 0.95±0.911 for treatment and control groups, respectively. On day 7 the average is 0.00±0.00 for treatment group and 0.37±0.496 for control group. Conclusion: Ozone water is able to stimulate and quicken the healing process for wounds and reduce the inflammation of the tooth socket.

Background: Cleft lip and palate is one of the most common congenital abnormalities in infants and is caused by more than one factors, which can be genetic and environmental. Defects in a family gene can result in cleft lip and palate. The study found a high family history relationship with the incidence of cleft lip and palate. Birth order studied by several researchers also has different results, which were influenced by folic acid consumption, maternal knowledge, lack of antenatal care visits and maternal age. To determine the cases of cleft lip and palate based on the birth order of the children and family history of the patients at Mitra Sejati General Hospital. Purpose: The study aimed to investigate cleft lip and cleft palate patients by birth order and family history. Methods: This research was a retrospective descriptive study using survey method. Researchers gave 13 questions through a questionnaire and data were collected and counted manually. Results: The results showed that based on the birth, the cleft case in the first birth order amounted to 25 people, the second 30 people, the third 19 people, and the fourth or more as many as 20 people. Based on family history, 27 patients had a family history of cleft lip and palate, while 67 patients did not have family history. Conclusion: The cases of clefts at Mitra Sejati General Hospital happened more frequently in the second child and most incidence did not have family history.