Androgenetic alopecia (AGA) is the most common type of alopecia, affecting up to 80% of males and 50% of females. 1 It is a chronic, progressive, noncicatricial, androgen-dependent condition that affects genetically predisposed individuals, leading to progressive follicular miniaturization. Currently, only topical minoxidil and oral finasteride are approved for its treatment. 2 2 | C A S E REP ORT A 47-year-old healthy white male patient came to our clinic with a complaint of hair loss. On examination, the patient had diffuse thinning on his scalp hair and recession of the frontal and temporal hairline (Hamilton-Norwood Scale IV) without evidence of inflammation or scarring (Figure 1A). He had a positive family history of hair loss, and extensive laboratory analyses were unremarkable. We made the diagnosis of male pattern AGA, and we started the gold-standard treatment with minoxidil 5% topical solution twice daily and finasteride 1mg daily for 2 years, with improvement during this period. However, after that, the patient's clinical response stabilized and he requested hair transplantation. After a discussion of all treatment options, we added mesotherapy, a minimally invasive technique, to his previous treatment, postponing the need for an invasive procedure. The patient received 10 sessions of sterile injectable blend containing 1ml minoxidil 0,5%, 1ml finasteride 0,05%, 2ml biotin 5mg/ml, and 2ml D-panthenol 50mg/ml (Pineda®

Background: Throughout history, wigs have often had a relevant cultural and social importance with correlations to wealth and position of power. Wigs help minimize the psychological consequences of different types of hair loss. They may reduce potential experiences of stigmatization, and improve social confidence and quality of life, besides enhancing self-esteem and social adjustment. In dermatology, wigs may have a positive impact on the global treatment of patients suffering from alopecia as they offer an immediate and efficient cosmetic result. However, the medical literature on wigs is not extensive. Aims: This review aims to discuss synthetic wigs and nonsynthetic custom-made hair systems, highlighting different hair fibers, foundations, various types of prosthesis, and the most common methods of attachments used to make wigs. Methods: The terms "wigs", "hair" AND "camouflage", "alopecia" AND "camouflage", and "hair prosthesis" were used to perform a literature search in MEDLINE through PubMed until April 8th, 2020. The search was limited to English-language peer-reviewed journal articles about humans, and it included only nonsurgical alternatives to camouflage alopecia. Conclusions: This article will help physicians, especially those who care for patients with hair loss, to provide appropriate advice for their patients about the wide variety and peculiarities of wigs and hairpieces currently available.

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Dermatite herpetiforme é uma dermatose autoimune caracterizada por lesões papulo vesiculosas pruriginosas e simétricas, que ocorrem com disposição herpetiforme. A doença tem patogênese multifatorial, dependendo de componentes genéticos, ambiental e imunológico. Há evidências que sugerem que fatores hormonais podem desempenhar um papel na doença. Os autores descrevem o caso de uma paciente do sexo feminino, 28 anos, com dermatite herpetiforme e enteropatia glúten sensível, cujas lesões cutâneas exacerbadas mensalmente durante o período menstrual, após interrupção do uso de anovulatório oral.

A esclerodermia juvenil é uma doença que apresenta características diferentes em comparação com a esclerodermia no adulto. Sua incidência é rara na infância. Pode ser sistêmica ou localizada, sendo esta última a mais comum. Relatamos um caso de esclerodermia juvenil em uma criança de 3 anos de idade do sexo feminino apresentando placa amarelada no tronco simulando uma lesão xantomatosa. O halo lilás ao redor da lesão ajudou na formulação correta da hipótese diagnóstica confirmada pela histopatologia. O diagnóstico precoce no caso em questão, possibilitou a instituição do tratamento em uma fase inicial da doença, contribuindo para um melhor prognóstico do paciente.