The A allele is associated with a worse outcome in response to the hypocaloric dietary intervention regarding abdominal circumference reduction; the same allele did not show interaction with any anthropometric outcomes in response to the exercise program applied.

In this study, we investigated the influence of two SNPs (rs846910 and rs12086634) of the HSD11B1 gene that encodes 11β-hydroxysteroid dehydrogenase type 1(11β-HSD1), the enzyme that catalyzes the conversion of cortisol to cortisone, on variables associated with obesity and metabolic syndrome in 215 individuals of both sexes from southern Brazil. The HSD11B1 gene variants were genotyped using the TaqMan SNP genotyping assay. Glucose, triglycerides, total cholesterol, HDL-cholesterol and LDL-cholesterol were measured by standard automated methods. Significant results were found in women, with carriers of the G allele of SNP rs12086634 having higher glucose levels than non-carriers. Carriers of the A allele of SNP rs846910 had higher levels of HDL-cholesterol. The involvement of both polymorphisms as independent factors in determining the levels of glucose and HDL-cholesterol was confirmed by multiple regression analysis (β = 0.19 ±0.09, p = 0.03 and β= 0.22 ± 0.10, p = 0.03, respectively). Our findings suggest that the HSD11B1SNPs studied may indirectly influence glucose and HDL-cholesterol metabolism in women, possibly through down-regulation of the HSD11B1 gene by estrogen.

The aim of this study was to evaluate physical fitness of Le Parkour practitioners in the city of Curitiba-PR. 13 male subjects (19.46 ± 2.82 years) who have been practicing the activity for more than six months participated in the study. Anthropometry and tests of physical fitness (back-and-forth 20-meter running, 1-minute abdominal, flexion and extension of the arms, vertical and horizontal push, sit-and-reach test and Wingate) were performed. The results were analyzed using descriptive statistics (mean and standard deviation) and are classified based on the reference tables for each test. After evaluating the VO2max, 53.85% of the practitioners were considered "low fitness" and 46.15% presented adequate cardiorespiratory fitness. Regarding strength /abdominal resistance, 46.15% of subjects were classified as "low fitness" and 53.85% as "recommended range". The peak power and average power were considered as "regular" in all subjects. The fatigue index was greater than or equal in 54% of subjects. Flexibility was assessed as "low fitness" in 69.23% of the sample. Assessment of strength / endurance of upper limbs presented 84.62% in the "recommended range". The results from this study suggest that Le Parkour, as an acyclic activity with emphasis on jumping and activities of strength in arms, led best values on tests of dynamic horizontal, vertical and strength of upper limbs. Meanwhile the other variables were below average, which should be considered in the prescription of exercises and the monitoring of individuals during the activity's practice. Further studies with larger samples and training control Le Parkour practitioners are suggested.

O objetivo deste estudo foi verificar a frequência de pressão arterial elevada em meninos e meninas de 10 a 16 anos de idade, analisando sua associação com o excesso de peso corporal e a obesidade abdominal. Foram avaliadas 764 crianças e adolescentes (365 meninos e 399 meninas) provenientes de cinco escolas da rede pública de Curitiba. Avaliaram-se a estatura, o peso corporal, a circunferência abdominal e as pressões arteriais sistólica e diastólica de repouso. Foram utilizados o teste t de Student e Qui-Quadrado. Para todas as análises considerou-se p<0,05. As frequências de pressão arterial elevada e de excesso de peso corporal nos escolares foram iguais a 18,6% e 30,8%, respectivamente. Em 33,1% dos alunos constatou-se obesidade abdominal. Neste estudo a prevalência de pressão arterial elevada constitui um fator a ser investigado. Palavras-chave: Pressão arterial. Escolares. Excesso de peso. Obesidade abdominal.

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