The most common primary malignancies that affect the pericardium are lung cancers. Typically, pericardial involvement stays undiagnosed, with almost 1-20% of all tumor-related autopsies revealing invasion of the pericardium. Pericardial effusions are seldom the first location of metastasis and presentation of a primary malignancy. Malignant pericardial effusions are usually silent, although they cause dyspnea, chest discomfort, arrhythmias, cough, and, in rare cases, pericardial tamponade. In a patient with tamponade, a high index of tumor-related suspicion is crucial to rule out cancer. Emergency pericardiocentesis is indicated based on the clinical presentation, however, the patient frequently has a bad prognosis regardless of whether treatment is administered or not. In this case series, we report five cases of non-small cell lung cancer (NSCLC) with pericardial effusion as an initial presentation.
The objective of this case report is to highlight the clinical, radiological, and histopathological features of a case of a 33-year-old male patient, who presented to AVBRH, Sawangi (Meghe), Wardha, with an anterior mediastinal mass with superior vena cava syndrome and after detailed studies was diagnosed as a case of germ cell tumor which was further confirmed on immunohistochemistry staining.
Pyopneumothorax is a common complication associated with tuberculosis, especially in patients with lung parenchymal cavitatory lesions. In this publication, we highlight the case of a 43-year-old female patient who presented with chief complaints of dry cough, left-sided chest pain, and dyspnea on exertion. An X-ray of the chest posteroanterior (PA) view, revealed a left-sided moderate pleural effusion with pneumothorax. Immediate intercostal chest drain (ICD) insertion was done and a pleural fluid cytology sample was sent which was suggestive of tubercular empyema and the patient was promptly initiated on anti-tubercular treatment to which she responded well and showed clinical and radiological improvements.
Pulmonary hydatid cyst is an exceptional cause of pyopneumothorax that should be considered in countries where hydatid disease is endemic. The documented rates of simple pneumothorax in patients with pulmonary hydatidosis ranges from 2.4-6.2%. Hydatidosis is a parasitic zoonosis of the genus Echinococcus that infects herbivores and humans in its larvae stage(hydatid) and in paediatric population, generally presents as pulmonary hydatidosis. Misdiagnosis of this condition as tubercular in origin can cause treatment and prognostic delays for the patient. We report a case of a 15 year old male presenting with complaints of breathlessness (Grade 2 MMRC) since 3 months and dry cough, low grade fever with chills since 3 months. He had previously received AKT therapy and IV antibiotics. His blood investigations were normal. His sputum for AFB, CBNAAT was negative. His initial chest xray was suggestive of right sided hydropneumothorax. CECT Thorax revealed features suggestive of hydatid cyst in right posterobasal segment lower lobe with loculated pyopneumothorax with collapsed and consolidated right lung with mediastinal lymphadenopathy. After admission, Intercostal chest drainage tube was inserted on the right side and connected to underwater seal and pleural fluid was drained. Pleural fluid investigations revealed exudative effusion by Lights criteria, ADA was 150, culture and sensitivity revealed no growth and cytology revealed features of empyema.The patient was started on IV Piperacillin+Tazobactam, IV Metronidazole and Tab Albendazole for 14 days along with AKT considering raised pleural fluid ADA levels as suggestive of tubercular pleural effusion. The patients hydatid serology (Echinococcus IgG Antibody ELISA- 0.88) came out to be positive which confirmed our diagnosis of hydatidosis. After repeat chest x ray, there was resolution noted in effusion and ICD tube was removed and the patient was discharged on oral antibiotics for 14 days and Tab Albendazole for 3 months.
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