Anterior mediastinal mass with superior vena cava syndrome: A rare presentation of germ cell tumor

Aurangabadkar, Gaurang; Lanjewar, Ajay; Jadhav, Ulhas; Mayekar, Mrinmayee; Ali, Saood; Wagh, Pankaj

doi:10.4103/jfmpc.jfmpc_153_22

Search citation statements

Order By: Relevance

Paper Sections

Select...

Clinical Presentation1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These symptoms are caused by large mediastinal masses, 6 that can rarely also lead to pericarditis 47 or seizures 48 . Other severe symptoms include haemoptysis, 49 superior vena cava syndrome 50 or cardiac thrombosis 51 . Few cases show systemic symptoms, including fever, nausea and hoarseness 52 .…”

Section: Clinical Presentationmentioning

confidence: 99%

Primary germ cell tumours of the mediastinum: A review with emphasis on diagnostic challenges

Fichtner,

Marx,

Ströbel

et al. 2023

Histopathology

View full text Add to dashboard Cite

This article will review current aspects of the histopathological, immunohistochemical and molecular analysis of primary mediastinal germ cell tumours (PMGCTs) as well as their aetiological, epidemiological, clinical and therapeutic features. PMGCTs represent an important differential diagnosis in the spectrum of mediastinal tumours, and their diagnosis is usually made on small tissue samples from core needle biopsies in combination with diagnostic imaging and serum tumour markers. As in lymphomas, a small biopsy is often the only viable tumour sample available from these patients, as they receive chemotherapy prior to eventual surgical resection. Pathologists therefore need to apply an efficient combination of immunohistochemical markers to confirm the diagnosis of a PMGCT and to exclude morphological mimics.

show abstract