Objetivo: Identificar por meio da literatura científica os impactos na qualidade de vida de pacientes adultos com Transtorno de Déficit de Atenção e Hiperatividade (TDAH) com diagnóstico tardio e ausência de tratamento. Métodos: Revisão de Literatura Integrativa realizada de julho até agosto de 2022, por meio de pesquisas nas seguintes bases de dados SciELO, PubMed e Lilacs. Foram encontrados 1346 artigos e selecionados, após os critérios de inclusão, 14 estudos para compor. Resultados: Os diferentes tipos de estudo analisados apontam para o fato de que, além da avaliação clínica e escala para diagnóstico do TDAH em adultos serem direcionados, com base na sintomatologia apresentada nessa faixa etária, os impactos na qualidade de vida desses pacientes são evidentes. Assim, a importância do diagnóstico evidencia-se pela necessidade de tratamento efetivo a fim de proporcionar maior qualidade de vida a tais pacientes. Considerações finais: Faz-se necessário ampliar o campo de pesquisas a respeito do transtorno de déficit de atenção e hiperatividade em pacientes adultos, com intuito de proporcionar maior compreensão dos impactos de vida gerados pelo transtorno, especialmente nos casos de diagnóstico tardio, para possibilitar, portanto, tratamento adequado e melhora da qualidade de vida.
Goal: Discuss the prognosis of pituitary adenomas considering their clinical consequences and resulting systemic changes, in addition to possible therapeutic measures for management. Method: Literature review carried out from October to November 2022, through searches in the Scielo and Pubmed databases with the descriptors "pituitary adenoma", "symptoms", "treatment" and "diagnosis". 2925 articles were found and, after the inclusion criteria, 13 studies were selected. Review: Pituitary adenoma (HA) is the second most common intracranial tumor in the population. HAs can be asymptomatic, oligosymptomatic or cause clinical repercussions for the patient, ranging from visual disturbances to infertility. In this context, the diagnosis of HAs can be complex and must be performed by interdisciplinary professionals, with magnetic resonance imaging being the gold standard exam for imaging diagnosis. Final Considerations: There are variants regarding the tumorextension, pace of evolution and degree of impact on surrounding structures -that must be taken into account in order to shape an individualized and effective planning for each patient.
Goal: To discuss, through the scientific literature, the association between the balance of the intestinal microbiota and the emergence of neurodegenerative disorders, especially Alzheimer's disease (AD). Methods: Literature review carried out from October to November 2022 through searches in the following PubMed database. 248 articles were selected and, after inclusion criteria, 17 studies were selected to compose this review. Review: The different studies analyzed indicate that the microbiota-intestine-brain axis is closely interconnected and involved in neural and brain functioning. Its participation consists of processes of cognitive regulation and aging processes, which are directly related to intestinal dysbiosis and its repercussions at the level of the central nervous system (CNS). Intestinal dysbiosis may be in the process of biological senescence and culminate in chronic systemic inflammation, with the potential for brain beta-amyloid aggregation. Final Considerations: There is an imbalance of the intestinal microbiota that is related to neurodegenerative diseases. As the pathophysiology of AD is multifactorial, it is still necessary to deepen studies on this relationship to aid in early diagnosis and treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.