Medicinal plants and plant extracts are the leading sources of quorum sensing inhibitors. Patents related to quorum sensing inhibitors are taking new leaps in medicine, especially applications relating to the addition of quorum sensing inhibitors on to the surface of implantable or indwelling devices that are helpful in eradicating the trouble of infection in health care industry.
Plants with medical properties are often enriched with endophytes that have the potential to produce important bioactive compounds. Endophytes after entering the plant tissue may either colonize a particular tissue or may spread throughout the host plant without causing damage. The possession of pharmaceutical and biological properties has made the Holostemma ada-kodien Schult as one of the widely used plants of medicinal importance in India. Following the direct cut method three endophytic bacterial strains (UC H1, UC H4 and UC H7) were isolated, identified and characterized from the healthy looking rhizome of H. ada-kodien. Among these isolates, UC H1 and UC H4 were found to have many properties like antibacterial compounds, hydrolytic enzymes and plant growth promoting traits. The isolate UC H4 have ability for Indole-3-Acetic Acid (IAA) production of 513.54 U/ml and very good protease and pectinase activities of 20.65 U/ml and 16.09 U/ml respectively. So far no reports are available on the endophytic microflora of H. ada-kodien.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.