To evaluate the Candida krusei and Candida albicans biofilm formation abilities on 5 different types of contact lenses and compare their metabolic activities and biomass. Methods: After biofilm formation by both the test species, their metabolic activity was assessed by the 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide reduction assay with menadione, while the biomass was determined by staining with 0.4% crystal violet dye for further statistical analysis. Results: Both the Candida species could form biofilms on different types of contact lenses, with greater metabolic activities and lower biomass formation in rigid gas permeable lenses. Conclusion: Biofilm formation with greater metabolic activity and greater biomass were expected on soft contact lenses considering their surface hydrophobicity. However, the results demonstrated a greater metabolic activity on rigid contact lenses. This result has a great significance with regards to the increasing risk of microbial keratitis, although further studies are warranted to better elucidate the formation of biofilms on different types of contact lens materials in the future.
Antiphospholipid antibody syndrome (APS) is characterized by the development of venous and/or arterial thrombosis and by gestational morbidity (recurrent fetal losses) in the presence of antiphospholipid antibodies. We report the case of a 38-year-old woman who was diagnosed with primary APS from thromboembolic abnormalities in the retinal periphery that led to retinal ischemia. The aim of this study is to share with physicians and medical undergraduates an atypical manifestation of the syndrome that is the most common acquired thrombophilia, that should be part of the diagnostic routine of all clinical specialties.
Juvenile xanthogranuloma is a rare benign non-Langerhans cell histiocytosis. Clinical manifestation usually occurs up to the age of 2 years, with yellowish papules and variable clinical progression. Approximately 0.75% of patients had systemic involvement and 0.25%, ocular alterations. The purpose of this report is to describe a case of a preschool 2-year-old female patient, with nodules in the upper right eyelid, 0.5-cm wide, with well-defined edges, an uncertain date of onset, a stable growth for 6 months, with no inflammatory signs, pruritus, pain, bleeding, or other similar lesions in the body. No further changes were observed in the physical examination. Histopathological examination of the specimen showed a skin lesion with histiocytoid, spindle-shaped cells and xanthomized cells, inflammatory infiltrate and numerous Touton giant cells. The result was compatible with diagnosis of juvenile xanthogranuloma. Therefore, the importance of including juvenile xanthogranuloma in the differential diagnosis of eyelid lesions is emphasized, especially in children.
A Liga Acadêmica de Oftalmologia, da Universidade Federal de Alfenas (UNIFAL-MG) é uma entidade que visa à difusão do ensino, realização de pesquisas e atividades de extensão em Oftalmologia. Com o objetivo de difundir o conhecimento sobre Oftalmologia, desenvolveu um curso à distância sobre o tema “Saúde Ocular na Atenção Básica”, abordando tópicos básicos acerca da anatomia e fisiologia dos olhos e de patologias oculares prevalentes na população, que devem ser dominadas pelo médico generalista, promovendo Educação em Saúde na área, especialmente para profissionais de saúde que atuam na atenção básica e estudantes. O curso contém 15 aulas desenvolvidas e ministradas pela docente coordenadora da Liga, médica oftalmologista, com a participação dos membros da Liga, acadêmicos de Medicina do segundo e quarto períodos da UNIFAL-MG. Os vídeos foram produzidos e editados no Centro de Educação Aberta e a Distância da UNIFAL-MG, sendo posteriormente disponibilizados na Rede Nacional de Ensino e Pesquisa e Plataforma Moodle e como disciplina optativa on line. No contexto da Educação em Saúde, baseada em plataformas digitais e novas tecnologias de informação, trata-se de uma iniciativa pioneira na área de Oftalmologia, pois envolveu tanto acadêmicos de Medicina quanto docente médica especialista na área, possibilitando, com uma linguagem simples e acessível, transmitir o conhecimento básico sobre tema altamente relevante.
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