ARTICLE INFORMATION Fill in information in each box below
Article Type
Research articleArticle Title (within 20 words without abbreviations) Effect of Saccharomyces cerevisiae boulardii on sows´ farrowing duration and reproductive performance, and weanling piglets´ performance and IgG concentration Running Title (within 10 words) Saccharomyces cerevisiae boulardii in sows and weanling piglets
The aim of this study was to assess the effect that feeding Saccharomyces cerevisiae boulardii CNCM I-1079 (LSB) to lactating sows and their progeny has on inflammatory response and mucosal immunity after vaccination against Actinobacillus pleuropneumoniae. Sixty-seven Danbred sows were allotted into two treatments when they entered the farrowing room seven days before the expected farrowing date: control (CON: lactation diet) and LSB (CON + 12 × 109 colony forming units (CFU)/d until weaning). At weaning, piglets were equally allotted into two experimental diets according to sow diet: control (CON: 2-phase post-weaning diets) and LSB (CON + 2 × 109 CFU/kg and 1 × 109 CFU/kg in phases 1 and 2, respectively). The piglets were vaccinated at days 26 and 49 post-weaning. Growth performance and number of IgA producing cells and cytokine’s gene expression in lung, lymph node, and intestine samples at day 70 post-weaning were assessed and analyzed in SPSS Statistics 26: performance with a general linear model with sex, room, sow diet, piglet diet, and their interactions as main effects, and immunity with a Kruskal–Wallis test for k unrelated samples. Piglets from LSB-fed sows displayed a higher average daily gain (ADG; p < 0.01) and a heavier body weight (BW; p < 0.05) during lactation, tended (p < 0.1) to be heavier at day 49, and to have a higher ADG between days 26 and 49; had fewer number of IgA producing cells in the lymph node (p < 0.05); and all the cytokines studied were significantly under-regulated (p < 0.05) in the lung. It is concluded that feeding Saccharomyces cerevisiae boulardii CNCM I-1079 to sows improved piglet performance during lactation and showed a clear reduction in the inflammatory status of the lungs after vaccination against A. pleuropneumoniae, suggesting that there was a maternal imprinting effect on mucosal protection and a cross-talk between the gut microbiota and the lung.
The transmission of passive immunity from the sow to the neonate piglets through colostrum is crucial for their future development. The aim of this experiment was to demonstrate that feeding the live yeast Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) increases the immunoglobulin G (IgG) concentration in colostrum. In total, 620 colostrum samples were taken from mixed-parity sows (1-9) in 11 farms in Colombia. There were 2 treatments: control (CON; standard feed in gestation and lactation), and SCB (CON + 1 × 109 colony forming units (CFU)/kg, fed from 3 weeks before the expected farrowing date). The samples were taken within the first 4 hours after the birth of the first piglet, from both sides of the teats of the sow, and immediately analyzed with a MA871 refractometer to obtain a °Brix value. Furthermore, each value was attributed to 1 of the 4 following categories regarding IgG concentration: Very good, Adequate, Limited, and Poor. Data were analyzed with SPSS Statistics 26.0 (IBM) and submitted to an analysis of variance with farm as random effect, parity rank and treatment as fixed effects, and their interactions. However, no interaction was found between any of the variables studied. Colostrum from sows in the SCB treatment displayed a higher °Brix value (P < 0.001) than the 1 from sows in the CON treatment. Additionally, the percentage of sows fitting the categories Very good and Adequate was greater in the SCB treatment than in the CON, and the one fitting the categories Limited and Poor was greater in the CON treatment than in the SCB. It is concluded that supplementing sows with Saccharomyces cerevisiae boulardii CNCM I-1079 from 3 weeks before farrowing increases IgG concentration in colostrum, helping the neonate piglets to acquire the passive immunity necessary to improve later performance.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.