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NFECTIONS ARE THE MOST COMMONcause of death in premature infants andamajorthreatforpooroutcomes. 1 Late-onset sepsis, ie, infections arising after the perinatal period, are mainly nosocomial and affect 21% of very lowbirth-weight (VLBW) (Ͻ1500 g) neonates, with many more undergoing empirical antibiotic treatment. 2 In VLBW neonates, the digestive tract is a major site for colonization and systemic translocation by many pathogens. Also, prolonged Author Affiliations and Task Force Members are listed at the end of this article.

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The Prechtl General Movement Assessment (GMA) has become a cornerstone assessment in early identification of cerebral palsy (CP), particularly during the fidgety movement period at 3–5 months of age. Additionally, assessment of motor repertoire, such as antigravity movements and postural patterns, which form the Motor Optimality Score (MOS), may provide insight into an infant’s later motor function. This study aimed to identify early specific markers for ambulation, gross motor function (using the Gross Motor Function Classification System, GMFCS), topography (unilateral, bilateral), and type (spastic, dyskinetic, ataxic, and hypotonic) of CP in a large worldwide cohort of 468 infants. We found that 95% of children with CP did not have fidgety movements, with 100% having non-optimal MOS. GMFCS level was strongly correlated to MOS. An MOS > 14 was most likely associated with GMFCS outcomes I or II, whereas GMFCS outcomes IV or V were hardly ever associated with an MOS > 8. A number of different movement patterns were associated with more severe functional impairment (GMFCS III–V), including atypical arching and persistent cramped-synchronized movements. Asymmetrical segmental movements were strongly associated with unilateral CP. Circular arm movements were associated with dyskinetic CP. This study demonstrated that use of the MOS contributes to understanding later CP prognosis, including early markers for type and severity.

Consistent and predominant cramped synchronized GMs specifically predict cerebral palsy. The earlier this characteristic appears, the worse is the later impairment.

ARE-METAL STENTING, BY DEcreasing the rate for targetvessel revascularization (TVR), 1,2 has been endorsed as a class I indication in the treatment of acute ST-segment elevation myocardial infarction (STEMI). 3 Abciximab, by virtue of its salutary effect on tissue perfusion and coronary artery patency, has also been recommended as part of a reasonable treatment strategy. 3,4 Sirolimus-eluting stents greatly reduce the need for TVR compared with bare-metal stents and thus have the potential to further improve long-term clinical outcome after primary percutane-For editorial comment see p 2154.

Preterm neonates had the highest rates of LOD and mortality. Most mothers carried GBS at the time of the LOD diagnosis, whereas 6% had mastitis. Intrapartum antibiotics were associated both with delayed presentation of symptoms and milder LOD.