An early marker for neurological deficits after perinatal brain lesions

Prechtl, H.F.R.; Einspieler, Christa; Cioni, Giovanni; Bos, Arend F.; Ferrari, Fabrizio; Sontheimer, Dieter

doi:10.1016/s0140-6736(96)10182-3

Cited by 574 publications

(618 citation statements)

References 16 publications

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“…Previously, Einspieler et al reported that impairment of the quality of the motor repertoire, especially around 3 months after term, is highly predictive of severe neurological sequelae (11,13). Of the five items on the Motor Optimality List, FM quality is the most reliable predictor of either severe neurological abnormalities or a normal neurological outcome (13,16). In our study, however, we found no difference in the quality of FMs between the two groups.…”

Section: Discussioncontrasting

confidence: 74%

“…The first and most important finding of our study was that HC infants had a higher MOS at 3 months after term than DXM infants. Previously, Einspieler et al reported that impairment of the quality of the motor repertoire, especially around 3 months after term, is highly predictive of severe neurological sequelae (11,13). Of the five items on the Motor Optimality List, FM quality is the most reliable predictor of either severe neurological abnormalities or a normal neurological outcome (13,16).…”

Section: Discussionmentioning

confidence: 99%

“…Normal GMs are characterized by complexity, variability, and fluency, whereas in abnormal GMs, these are reduced (12). The quality of the fidgety general movements (FMs), present between 9 and 20 weeks after term and defined as continuous small movements of moderate speed in all directions, is a particularly accurate marker for neurological outcome: most infants (96%) with normal FMs have normal neurological outcomes, whereas most infants (95%) in whom FMs are absent during this period develop cerebral palsy (13). Recent studies reported that detailed aspects of GMs, expressed as a motor optimality score (MOS), also have predictive value for mild motor abnormalities later on (14,15).…”

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Hydrocortisone vs. dexamethasone treatment for bronchopulmonary dysplasia and their effects on general movements in preterm infants

et al. 2011

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INTRODUCTION: hydrocortisone (hc) and dexamethasone (DXM) are used to treat preterm infants at risk for bronchopulmonary dysplasia (BPD). This may, however, affect their longterm neurological development. We aimed to determine the effect of hc and DXM therapy in preterm infants on neurological functioning as assessed by the quality of general movements (GMs) until 3 months after term. RESULTS: We found no difference in the quality of GMs between hc and DXM infants until term age. at 3 months, hc infants had a higher median motor optimality score (MOs) than DXM infants (25 vs. 21, P = 0.015). In the DXM group, MOs on the first day of treatment was lower than before treatment (10 vs. 11, P = 0.030). DISCUSSION: MOs decreased in DXM infants on the first day following treatment and at 3 months after term. This was not the case in hc infants. Our study suggests that neurological functioning at 3 months after term is better in infants treated with hc than in infants treated with DXM. METHODS:We performed a longitudinal, observational study including 56 preterm infants (n = 17 hc, n = 17 DXM, n = 22 controls). GM quality, videoed before and after treatment, was assessed. In addition, a MOs was assigned to details of the GMs.

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Section: Discussioncontrasting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Hydrocortisone vs. dexamethasone treatment for bronchopulmonary dysplasia and their effects on general movements in preterm infants

et al. 2011

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“…Predictive accuracy of GMA during the FMs' period for later CP has been reported to be very high (13,28), and inter-rater reliability appears to be high (15,16). A recent report from Australia showed very high sensitivity and specificity for abnormal development at 1 year when GMA was assessed by several observers in a structured GMA network (13).…”

Section: Discussionmentioning

confidence: 99%

Computer-based video analysis identifies infants with absence of fidgety movements

et al. 2017

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“…[71][72][73][74][75][76] Since this test is based solely on visual observation, it has received some criticism because it allows for differences in the results when the same child is observed by different assessors. The training necessary for the practical administration of the test is quite expensive and requires greater efforts from those interested in administering it.…”

Section: Gmmentioning

confidence: 99%

Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avaliação

Santos

Araujo²,

Porto³

2008

J. Pediatr. (Rio J.)

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Objective: To review the literature regarding screening psychomotor tests for the early identification of developmental problems. Sources:A search on SciELO, PubMed and Google Scholar was performed using the terms "prematurity," "developmental delay," "cerebral palsy," "early diagnosis" and "evaluation tests." Summary of the findings:A total of 455 references were listed, and 174 studies were selected for this review based on title, relevance, and abstract. Only original and electronically available material, from 1985 forward, with information on design, applicability, and psychometric properties of those tests was included. Conclusions:Screening tests are important to speed the beginning of treatment measures in order to allow for better developmental outcome. Among the many tests that can be employed for this purpose, the DENVER II and the Alberta Infant Motor Scale are the most often used in Brazilian studies. The Movement Assessment of Infants is starting to be used in our country. Two other tests are recommended in the literature due to their high sensibility and specificity:the Test of Infant Motor Performance and the General Movements.J Pediatr (Rio J). 2008;84(4):289-299: Prematurity, motor delay, early diagnostic, screening tests.

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An early marker for neurological deficits after perinatal brain lesions

Cited by 574 publications

References 16 publications

Hydrocortisone vs. dexamethasone treatment for bronchopulmonary dysplasia and their effects on general movements in preterm infants

Hydrocortisone vs. dexamethasone treatment for bronchopulmonary dysplasia and their effects on general movements in preterm infants

Computer-based video analysis identifies infants with absence of fidgety movements

Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avaliação

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