Forty eight extracts of four plants of the family Combretaceae were screened for antibacterial activity against standard organisms as well as clinical isolates. The extracts in different solvent systems showed high activity against both standard organisms and clinical isolates. Phytochemical screening revealed that the plants were very rich in tannins to which antibacterial activity may be attributed.
5-Nitrofuran derivatives were synthesized and their antibacterial activity was investigated using standard bacterial strains and clinical isolates. The compounds showed inhibitory effects on both Gram-positive and Gram-negative organisms.
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