Biological Activity of Methanolic Extract of Waltheria indica Roots

Osman, Raga Eltayeb; Elnima, Elamin Ibrahim; Omer, Mohammed Elfatih Ahm

doi:10.3923/jms.2013.471.476

Cited by 3 publications

(3 citation statements)

References 3 publications

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“…Ethanol extract of Waltheria indica had the ability to inhibit S. aureus, E. faecalis, E. coli [8,16,17], in which the leaf extract was the most active. The aqueous extract was resistant to S. aureus, E. faecalis, E. coli [8,18,19]. The aqueous extract from the roots had the best inhibitory effect on P. aeruginosa [18].…”

Section: Discussionmentioning

confidence: 97%

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Antibacterial properties of alcohol and water extracts of Waltheria indica (L.) plants collected from Binh Thuan province, Vietnam

Mahaxay¹,

Thanh²,

Vu³

et al. 2022

GSC Biol. and Pharm. Sci.

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This study aimed to investigate the antibacterial ability of Waltheria indica species collected from two communes of Phan Thiet city, Binh Thuan province. Research methods included making ethanol extracts and decoction and investigating their ability to inhibit bacteria through agar well diffusion method and determining the minimum inhibitory concentration (MIC). The results showed that the ethanol extract was resistant to 5 tested strains of bacteria (Bacillus cereus, Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa, Escherichia coli) with diameters of bacterial inhibition zones ranging from 6.76 to 14.50 mm, in which the resistance to Gram-positive strains was better than Gram-negative strains. The decoction inhibited only 3/5 of the tested bacterial strains (S. aureus, E. faecium, E. coli) with MICs from 125 to 750 mg/mL (dry weight of plant per volume of decoction). The antibacterial activities of extracts from the stems, leaves, and roots of the plants were different. Samples obtained from the 2 sites also showed different antibacterial capacities.

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Section: Discussionmentioning

confidence: 97%

“…The aqueous extract was resistant to S. aureus, E. faecalis, E. coli [8,18,19]. The aqueous extract from the roots had the best inhibitory effect on P. aeruginosa [18]. In particular, the aqueous extract was resistant to E. coli with a ring diameter of up to 31 mm [19].…”

Section: Discussionmentioning

confidence: 98%

Antibacterial properties of alcohol and water extracts of Waltheria indica (L.) plants collected from Binh Thuan province, Vietnam

Mahaxay¹,

Thanh²,

Vu³

et al. 2022

GSC Biol. and Pharm. Sci.

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show abstract

“…The aqueous, ethanol, methanol, and acetone extracts were tested against Bacillus pumilus, Enterococcus faecalis, E. coli, Shigella dysenteriae, Staphylococcus aureus, and found aqueous extract had good minimal inhibition concentration (MIC), and the zones of inhibition were dose-dependent [37,58,78]. One hundred milligrams per milliliter of root methanolic extract had 91.7% antibacterial activity against the clinical isolates (Klebsiella pneumonia, P. aeruginosa, S. aureus, Staphylococcus epidermidis) obtained from diabetic wound infection [79].…”

Section: Anti-bacterial Activitymentioning

confidence: 99%

Ethnobotanical, phytochemistry, and pharmacological property of Waltheria Indica Linn

Nirmala

Sridevi

2021

Futur J Pharm Sci

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Background In modern therapeutics, various human pathological disturbances were treated with the plant-based products. Waltheria indica Linn, a perennial herb, was commonly used in traditional medicine worldwide against various ailments such as cough, dysentery, diarrhea, bladder disorder, hemoptysis, inflammations, neuralgia, wounds, and ulcers. Main body The shrub was majorly distributed in tropical, subtropical regions and exists in many distinct local forms. Both the crude extracts and purified compounds from the whole plant and its parts showed wide pharmacological properties like antioxidant, analgesic, sedative, anti-bacterial, anti-fungal, and anti-parasitic. The phytochemical profile and traditional usage highlight the potency of the plant in the treatment of microbial infections and inflammatory diseases. Yet, additional studies are required for the confirmations of its traditional uses against other diseases. More detailed understanding of anti-cataract, anti-diabetics, asthma, anemia, and anti-cancer mechanism has to be explored. Though many research articles on the proposed plant are available, there has been a rising concern in the therapeutic property, especially on the alkaloids and flavonoids from this plant for drug design. Conclusion This article aims in a systematic and updated review on distribution, botany, traditional uses, phytocompounds, and relevant biological activities from each part of the plant. The information was collected from databases like PubMed, ScienceDirect, Web of Science, Google Scholar, books, dissertation, and reports via academic libraries that included more than 100 articles published since 1937. This ethnopharmacological study of the plant may create new insight into drug discovery to develop important novel leads against various biological targets.

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In vitro antimicrobial and antioxidant activities of certain brackish water cyanobacteria from Chilika Lake, India

Parida

Dash

Rath

2021

Vegetos

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Biological Activity of Methanolic Extract of Waltheria indica Roots

Cited by 3 publications

References 3 publications

Antibacterial properties of alcohol and water extracts of Waltheria indica (L.) plants collected from Binh Thuan province, Vietnam

Antibacterial properties of alcohol and water extracts of Waltheria indica (L.) plants collected from Binh Thuan province, Vietnam

Ethnobotanical, phytochemistry, and pharmacological property of Waltheria Indica Linn

In vitro antimicrobial and antioxidant activities of certain brackish water cyanobacteria from Chilika Lake, India

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