Conclusion: These data illustrate that if clonality assessment of PC is included in disease monitoring, the use of polyclonal over monoclonal antibodies is preferred for the detection of intracellular immunoglobulin light chains.
Gellan/trehalose layers were tailored to optimize on-chip storage and release of antibodies in a simple point-of-care CD4 counting chip with excellent agreement with standard methods.
These data illustrate when antibodies against SIg light chains are employed for B-cell clonality assessment, polyclonal antibodies are preferred over monoclonal antibodies.
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