This pilot study shows that periodontal disease significantly affects the serum levels of lipoproteins and suggests that following successful periodontal treatment decreases serum lipid concentration. This study suggests also that lipoproteins are possible intermediate factors that may link periodontal disease to elevated cardiovascular risk.
Periodontal regeneration is considered to be biologically possible but clinically unpredictable. In periodontitis, inflammation manifests clinically as loss of supporting periodontal tissues and regeneration of damaged tissue is the main goal of treatment. For decades, periodontists have sought to repair the damage through a variety of surgical procedures, and use of grafting materials and growth factors, and of barrier membranes. Reports have emerged that demonstrate which populations of adult stem cells reside in the periodontal ligaments of humans and other animals. This opens the way for new cell-based therapies for periodontal regeneration. This review provides an overview of adult human stem cells and their potential use in periodontal regeneration.
Objective: To evaluate the effect of periodontal treatment on gingival overgrowth in a group of renal transplant patients. Subjects and Methods: Twenty-five renal transplant recipients receiving immunosuppressive therapy with cyclosporine A (CsA) were randomly assigned to 2 groups. Group 1 (n = 15) included patients who had been specifically referred to a dental clinic to prevent gingival overgrowth and were given full periodontal therapy. Group 2 (n = 10) was comprised of patients who did not receive any professional periodontal cleaning. Patients from both groups were examined to determine their periodontal status before and after 3, 6 and 12 months in terms of their plaque index, gingival index and gingival overgrowth. During the examination, their overall health was stable. Results: For group 1, the scores were 1.89 (baseline), 0.98 (6 months) and 0.56 (12 months), and hence there were significant reductions (p = 0.0001). The gingival indices were 1.71 (baseline), 0.76 (6 months) and 0.35 (12 months), and the reductions were also significant (p = 0.0001). A significant association was observed between poor oral hygiene and the degree of gingival overgrowth. The 1-year post-treatment follow-up showed that patients in group 1 did not develop gingival overgrowth due to the use of CsA as group 2 did without prior periodontal therapy. Conclusion: Oral hygiene status was the most important variable related to the development and degree of gingival overgrowth due to the use of CsA.
This study confirms a significant relationship between periodontal disease, regardless its intensity, and blood lipid levels in the studied population. The results imply that periodontitis may be a risk factor and may contribute to the pathogenesis of atherosclerosis and cardiovascular diseases (CVD). However, future prospective randomized studies have to determine whether periodontal disease is a risk factor for the occurence of CVD.
Uvod: Alergija je neuspešan odgovor organizma protiv stranih antigena. Ponovno uvođenje iste strane materije u organizam izaziva reakciju koja dovodi do uništavanja sopstvenog tkiva. Alergijske reakcije se mogu izraziti u različitim organima i u bilo kojoj starosnoj grupi. Materijal i metode: U ovom radu učestvovalo je 84 pacijenta. Dijagnoza je zasnovana na pozitivnoj anamnezi preordiniranja leka, ugriza insekata, ranijih alergijskih reakcija, kao i tipične kliničke slike. Pratile su se varijante alergijskih promena , kao i najčešći uzroci njihove pojave. U potrazi za najčešćim alergenima, lekovi u stomatološkoj praksi takođe su smatrani potencijalnim pokretačima alergijskih događaja. Rezultati: Najčešći oblik alergijske reakcije bio je Stomatitis allergica i Enanthema fixum, sa lokalizacijom na dorzalnoj površini jezika i sluzokožom obraza. Skoro polovina registrovanih pacijenata prijavila je promenu nakon uzimanja odgovarajućeg leka iz grupe sulfonamida i penicilina. Zaključak: Ako je uzrok alergija poznat, prevencija kontrole alergijske reakcije je na prvom mestu. Visoka prevalenca alergijskih bolesti, poboljšane dijagnostičke procedure i tretmani imali su veliki uticaj na pružanje medicinske zaštite pacijentima sa alergijom. Ponekad možda neće biti moguće potpuno izbeći alergijsku reakciju , ali ovi koraci mogu pomoći u sprečavanju budućih alergijskih reakcija. Lekari treba da usvoje jasne nazive alergijskih poremećaja i pridržavaju se nomenklature u njihovoj profesionalnoj i javnoj komunikaciji.
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