In this study, we evaluated the effects of high-intensity swimming in an experimental model of acute lung injury (ALI) induced by lipopolysaccharide (LPS) on lung inflammation and antioxidant defenses. Balb/C male mice were submitted to exercise (30 min/day, 5 days/week, for a period of 3 weeks) prior to LPS instillation in the lung. Twenty-four hours after delivery of LPS (10 μg/animal), mice were euthanized and bronchoalveolar fluid (BALF) was obtained for cell counting and analysis of cytokines by ELISA. Lung tissue was used to evaluate antioxidant defenses. LPS instillation resulted in an increase in total and mononuclear cells, IL-1β, TNF-α, and IL-6 in BALF. LPS instillation also altered IL-10 and IL-ra levels in BALF and induced antioxidant defenses (glutathione, superoxide dismutase, catalase, and glutathione peroxidase) in the lung. Protein carbonyl increased in the LPS-treated animals. High-intensity swimming prevented all these changes induced by LPS. Significance: Therefore, this experimental protocol of high-intensity swimming showed a protective effect on ALI, decreasing inflammatory processes and preventing disturbances in antioxidant defenses into the lungs.
Geneva® rootstocks in Brazil are known to be efficient in controlling vigor, and are precocious and resistant to diseases. The objective of this study was to evaluate the performance of apple tree cultivars grafted on the Geneva® rootstocks in severe replant disease areas, by planting 60 days after the eradication. The experiments were implemented in 2017, in São Joaquim and Vacaria. The Gala Select and Fuji Suprema cultivars were grafted onto ‘G.202’, ‘G.814’, ‘G.210’, and ‘G.213’ rootstocks in the Tall Spindle training system. In 2018/2019, total thinning was carried out to promote plant growth. In São Joaquim, partial thinning was carried out in 2019/2020 harvest of ‘Gala Select’. The rootstocks were divided into two groups based on vigor, for both areas and cultivars. ‘G.202’ and ‘G.213’ were 40% less vigorous than ‘G.210’ and ‘G.814’. For ‘Gala Select’, the extreme non-fallow condition mainly affected the vigor and productivity of ‘G.213’ in both areas. At the end of two harvests, ‘G.213’ was 17% less productive than ‘G.210’, contrary to what is observed in areas where the fallow period is respected. However, ‘G.213’ confirmed a greater yield efficiency, which was 27% higher than ‘G.210’. This suggests that a perspective of forecasting production for the third crop is higher for ‘G.213’ than for ‘G.210’. In the case of ‘Fuji Suprema’, the G.210 rootstock was the most productive in both areas. In São Joaquim, ‘G.202’ matched ‘G.210’ in productivity and efficiency as it sprouts better in colder regions. Considering the fruit quality, ‘G.213’ anticipated the maturation with fruits of larger size and higher total soluble solids (TSS) in both areas and cultivars, making it possible to anticipate the harvest. It was concluded that the non-fallow condition does not alter the relative differences in vigor and fruit quality among the rootstocks. However, notwithstanding the overall replant tolerance of these rootstocks, it does reduce productivity by mainly affecting less vigorous rootstocks that need about three crops to overcome the allelopathic effects of the soil and start growing normally. The G.210 semi-dwarfing rootstock is an alternative for the immediate conversion of apple orchards of Gala Select and Fuji Suprema cultivars in southern Brazil.
Age is the main risk factor for developing breast cancer and clinically, older women have a more difficult rehabilitation process. Objective: The aim of the study was to evaluate the effects of physiotherapy intervention in range of motion (ROM) of shoulder and thermographic map of elderly postoperative treatment of breast cancer. Methods: A total of 10 elderly, undergoing surgery for breast cancer. The evaluation was done before and after the intervention by means of the goniometer for ADM measures and thermographic camera Eletrophysics PV320T, to identify the temperature of the thoracic region. We used the Wilcoxon test and Spearman correlation, with a 0.05 significance level. Results: The patients showed significant improvement in range of all movements of the affected limb, except internal rotation. When comparing the assessment of temperature values with the revaluation, there was an increase in temperature of the thoracic regions, and only significant values preserved breast. By comparing the temperature of the region preserved with compromised in the evaluation, there was a significant difference, since the revaluation, there was an approximation of these values. Conclusion: The correlation between increased temperature and ADM was significant for both members adduction and internal rotation member preserved in the evaluation. Intervention assured resolution or reduction of amendments on physical examination, improved ROM, increased temperature of the thoracic regions, and correlation between temperature increase and ROM bilateral adduction and internal rotation member preserved in the initial evaluation.
Introdução: O câncer de mama é incidente em idosas. A cirurgia destaca-se como tratamento, com possibilidade de lesões nervosas responsáveis por alterações sensitivas. Objetivo: avaliar os efeitos da fisioterapia na sensibilidade cutânea e mapa termográfico de idosas no pós-operatório do tratamento do câncer de mama. Métodos: Avaliadas 9 mulheres antes e após 15 sessões de fisioterapia, através dos monofilamentos de Semmes-Weinstein e da câmera termográfica. Os testes Wilcoxon e correlação de Spearman foram utilizados. Resultados: Após a intervenção houve aumento da temperatura em todos os quadrantes. Não houve relação significativa entre temperatura e sensibilidade. Em relação à sensibilidade antes e depois da intervenção, a diferença foi significante nos quadrantes superior externo (p=0,038) e inferior externo (p=0,007) da mama preservada e no superior externo da mama comprometida. Não houve correlação entre a região operada e não operada em relação à sensibilidade e temperatura. Conclusões: A intervenção promoveu aumento da temperatura local, induzindo à melhora no limiar de sensibilidade das pacientes.
Introdução: O carcinoma mamário se desenvolve devido à divisão desordenada de células. A principal forma de tratamento é a cirurgia, sendo a dor um dos fatores decorrentes. Objetivos: Avaliar os efeitos da fisioterapia na dor e mapa termográfico de idosas submetidas à cirurgia de câncer de mama. Material e métodos: Estudo quantitativo, quase-experimental, realizado com 10 idosas submetidas à cirurgia. A avaliação foi feita antes e após a intervenção pelo questionário de dor McGill e a câmera termográfica Eletrophysics PV320T para a identificação da temperatura corporal na região torácica das pacientes. Utilizou-se para análise o teste Wilcoxon e a correlação de Spearman, com nível de significância de 0,05. Resultados: Houve redução da dor nos locais avaliados, com exceção da região axilar. Do questionário de dor McGill, a parte física caracterizou maior diminuição quando comparadas a avaliação inicial e final. No escore total, a diferença foi significante. Entre os momentos de avaliação, houve aumento significativo da temperatura da área operada e preservada. Houve correlação significativa entre o domínio avaliativo e temperatura na avaliação inicial. Conclusão: A fisioterapia diminuiu a dor e alterou o mapa termográfico das pacientes deste estudo.Palavras-chave: câncer de mama, fisioterapia, termografia.
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