Christopher J. Coulson scite author profile

Cholera toxin CT, an enterotoxin produced by Vibrio cholerae, is responsible for the clinical manifestation of cholera which is characterized by severe fluid loss from the small intestine. The toxin acts by irreversibly stimulating adenylate cyclase in the basolateral membrane of the intestinal cell to raise cyclic AMP levels (Kimberg et al., 1971 ; Sharp & Hynie, 1971). CT is a 84000-M, protein composed of two types of

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Christopher J. Coulson

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