With support from the US National Tsunami Hazard Mitigation Program (NTHMP), the authors have been developing tsunami inundation maps for the upper US East Coast (USEC), using high-resolution numerical modeling. These maps are envelopes of maximum elevations, velocity, or momentum flux, caused by the probable maximum tsunamis identified in the Atlantic oceanic basin, including from far-field coseismic or volcanic sources, and near-field Submarine mass failures (SMFs); the latter are the object of this work. Despite clear field evidence of past large-scale SMFs within our area of interest, such as the Currituck slide complex, their magnitude, pre-failed geometry, volume, and mode of rupture are poorly known. A screening analysis based on the Monte Carlo simulations (MCS) identified areas for possible tsunamigenic SMF sources along the USEC, indicating an increased level of tsunami hazard north of Virginia, potentially surpassing the inundation generated by a typical 100-year hurricane storm surge in the region, as well as that from the most extreme far-field coseismic sources in the Atlantic; to the south, the MCS indicated that SMF tsunami hazard significantly decreased. Subsequent geotechnical and geological analyses delimited four high-risk areas along the upper USEC where the potential for large tsunamigenic SMFs, identified in the MCS, was realistic on the basis of field data (i.e., sediment nature and volume/availability). In the absence of accurate site-specific field data, following NTHMP's recommendation, for the purpose of simulating tsunami hazard from SMF PMTs, we parameterized an extreme SMF source in each of the four areas as a so-called Currituck proxy, i.e., a SMF having the same volume, dimensions, and geometry as the historical SMF. In this paper, after briefly describing our state-of-the-art SMF tsunami modeling methodology, in a second part, we parameterize and model the historical Currituck event, including: (1) a new reconstruction of the SMF geometry and kinematics; (2) the simulation of the resulting tsunami source generation; and (3) the propagation of the tsunami source over the shelf to the coastline, in a series of nested grids. A sensitivity analysis to model and grid parameters is performed on this case, to ensure convergence and accuracy of tsunami simulation results. Then, we model in greater detail and discuss the impact of the historical Currituck tsunami event along the nearest coastline where its energy was focused, off of Virginia Beach and Norfolk, as well as near the mouth of the Chesapeake Bay; our results are in qualitative agreement with an earlier modeling study. In a third part, following the same methodology, we model tsunami generation and propagation for SMF Currituck proxy sources sited in the four identified areas of the USEC. Finally, as an illustration of our SMF tsunami hazard assessment work, we present detailed tsunami inundation maps, as well as some other products, for one of the most impacted and vulnerable areas, near and around Ocean City, MD. We find that...

No abstract

Abstract-In this work we experimentally demonstrate (a) that the holding strength of universal jamming grippers increases as a function of the jamming pressure to greater than three atmospheres, and (b) that jamming grippers can be used for deep sea grasping tasks in ambient pressures exceeding one hundred atmospheres, where such high jamming pressures can be readily achieved. Laboratory experiments in a pressurized, water filled test cell are used to measure the holding force of a 'universal' style jamming gripper as a function of the pressure difference between internal membrane pressure and ambient pressure. Experiments at sea are used to demonstrate that jamming grippers can be installed on, and operated from, remotely operated vehicles (ROVs) at depths in excess of 1200m. In both experiments, the jamming gripper consists of a latex balloon filled with a mixture of fresh water and ~200 micron glass beads, which are cheaply available in large quantities as sand blasting media. The use of a liquid, rather than gas, as the fluid media allows operation of the gripper with a closed loop fluid system; jamming pressure is controlled with an electrically driven water hydraulic cylinder in the lab, and with an oil hydraulic driven large-bore water hydraulic cylinder at sea.

No abstract

No abstract

No abstract

No abstract

While treatment options are available, excessive daytime sleepiness (EDS) remains a significant unmet medical need for many patients. Relatively little rodent behavioural pharmacology has been conducted in this context to assess potential pro-vigilant compounds for their ability to restore functional capacity following experimentally induced sleep loss. Male Wistar rats were prepared for electroencephalographic (EEG) recording and subject to 11 h of sleep restriction using a biofeedback-induced cage rotation protocol. A simple response latency task (SRLT) was used to behaviourally index sleep restriction and the effects of pro-vigilant compounds: modafinil, d-amphetamine, caffeine, and the mGlu5-positive allosteric modulator LSN2814617. Sleep restriction resulted in a consistent, quantified loss of non-rapid eye movement (NREM) and REM sleep that impaired SRLT performance in a manner suggestive of progressive task disengagement. In terms of EEG parameters, all compounds induced wakefulness. Amphetamine treatment further decreased SRLT performance capacity, whereas the other three compounds decreased omissions and allowed animals to re-engage in the task. Caffeine and modafinil also significantly increased premature responses during this period, an effect not observed for LSN2814617. While all compounds caused compensatory sleep responses, the magnitude of compensation observed for LSN2814617 was much smaller than would be predicted to result from the prolongation of wakefulness exhibited. Using simple response latencies to index performance, an mGlu5 PAM dramatically increased wakefulness and improved functional capacity of sleep-restricted animals, without eliciting a proportionate compensatory sleep response. This effect was qualitatively distinct from that of amphetamine, caffeine and modafinil.Electronic supplementary materialThe online version of this article (doi:10.1007/s00213-015-3936-8) contains supplementary material, which is available to authorized users.