Wild rodents, such as the lowland paca (Cuniculus paca), capybara (Hydrochoerus hydrochaeris), rock cavy (Kerodon rupestris), guinea pig (Cavia aperea), and black-rumped agouti (Dasyprocta prymnolopha) are intensely hunted throughout Amazonia and at the semiarid regions of northeastern Brazil. To contribute to the preservation of these species, more information about their anatomy, physiology and pathophysiology is needed. The aim of this study was to standardize the vertebral heart scale (VHS) and cardiothoracic ratio (CTR) in clinically normal black-rumped agouti, as well as to compare the results of these two methods, which are commonly used to evaluate the cardiac silhouette in domestic animals. Twelve healthy black-rumped agoutis, divided into two groups (six males and six females), obtained from the Nucleus for Wild Animal Studies and Conservation at the Federal University of Piauí, were radiographed in right and left lateral and dorsoventral projections. The values of the VHS were 8.00±0.31v (the number of thoracic vertebral length spanned by each dimension, starting at T4) for males and 8.11±0.41v for females, and there was no statistical difference between the decubitus (right and left) or between males and females (P>0.05). The CTR mean values obtained were 0.51±0.03 for males, and 0.52±0.02 for females, and there was no statistical difference between the genders (P>0.05). However, there was positive correlation between VHS and CTR (r=0.77 right decubitus and r=0.82 left decubitus). The thoracic and heart diameter had mean values of 6.72±0.61 and 3.48±0.30 cm (males), and for the females, it was 6.61±0.51 and 3.5±0.30 cm, respectively, and there was statistical difference between the genders. The results demonstrated high correlation between the VHS and CTR producing similar results, indicating similar clinical precision for assessing the size of the cardiac silhouette in the black-rumped agoutis.

One herein reports a successful case of celiotomy by plastrotomy for removal of foreign bodies in yellow-footed tortoise (Geochelone denticulata). The animal was treated at the Veterinary Hospital of the Federal University of Piaui, with appetite loss, regurgitation, constipation, lethargy, reluctance to walk and slightly reddish ocular mucous membranes. Radiographic examination was performed, confirming the presence of foreign bodies in the stomach. The tortoise underwent celiotomy by plastrotomy for the removal of the foreign bodies. The opening of the plastron was performed through the abdominal shields, with the aid of a circular mini grinding saw. One performed an incision in the midline between the two abdominal veins to access the abdominal cavity. A gastrotomy for removal of the foreign bodies (nails, toothpicks, stones, pieces of plastic, glass and crockery pieces) was performed after the location of the stomach. The surgery was successful and confirmed with radiographic evaluation in the immediate postoperative period. The celiotomy by plastrotomy for removal of foreign bodies in that animal proved to be a viable, very important and safe technique to the survival of chelonians.

RESUMO.A ectopia ureteral é uma anomalia congênita do trato genito-urinário caracterizado por um distúrbio na inserção do ureter na vesícula urinária, sendo a causa mais comum de incontinência urinária em cães jovens, ocorrendo predominantemente em animais do sexo feminino. Anatomicamente é classificada como intramural ou extramural. Na intramural o ureterse anexa na superfície dorsal vesícula urinária, porém há falha ao desembocar no trígono vesical, enquanto que na extramural ocorre um desvio por completo da bexiga, podendo ocorrer em ambos os casos de forma unilateral ou bilateral. Os principais sinais clínicos incluem além da incontinência urinária, o eczema vulvar com hiperpigmentação, hipotricose e dermatite na região perivulvar, hematúria, piúria e cistites recorrentes. Objetivou neste artigo relatar o caso clínico de uma cadela da raça pinscher, 8 meses de idade, atendida no Hospital Veterinário da UFPI, diagnosticada e tratada para ectopia ureteral com megaureter e hidronefrose adquirida.Palavras chave: Ectopia ureteral, megaureter, hidronefrose, cão. Megaureter and hydronephrosis by extramural ureteral ectopia in dogABSTRACT. Ureteral ectopia is a congenital abnormality of the genito-urinary tract disorder characterized by the insertion of the ureter in the urinary bladder, the most common cause of urinary incontinence in young dogs, occurring predominantly in female animals. Anatomically it is classified as intramural or extramural. In the intramural ureter is attached to the dorsal surface of the urinary bladder, but has failed to culminate in the trigone, while the extramural there is a deviation in full bladder and can occur in both cases unilaterally or bilaterally. The main clinical signs include addition of urinary incontinence, vulvar eczema with hyperpigmentation, hypotrichosis and dermatitis in perivulvar region, hematuria, pyuria and recurrent cystitis. The objective of this article report the case of a bitch pinscher breed, 8 months old, attended at the Veterinary Hospital of UFPI, diagnosed and treated for ureteral ectopia with megaureter and acquired hydronephrosis.Keywords: Ureteral ectopia, megaureter, hydronephrosis, dog. IntroduçãoO Sistema urinário é composto pelos os rins, ureteres, bexiga e uretra. A função dos rins é produzir a urina que, por meio dos ureteres, chega à bexiga, onde é temporariamente armazenada. Os ureteres transportam urina dos rins para a bexiga e chegam a estes pelo hilo, onde se conectam a pelve renal ou estrutura equivalente, de acordo com a espécie animal.A inserção do seguimento final do ureter entre a musculatura vesical previne refluxo de urina para os ureteres quando aumenta a pressão intravesical (Feitosa, 2014).A diferenciação anormal dos ductos mesonéfricos e metanéfricos durante a gênese

In vitro senescence of multipotent cells has been commonly associated with DNA damage induced by oxidative stress. These changes may vary according to the sources of production and the studied lineages, which raises questions about the effect of growing time on genetic stability. This study is aimed at evaluating the evolution of genetic stability, viability, and oxidative stress of bone marrow mesenchymal stem cells (MSCBMsu) and renal progenitor cells of the renal cortex (RPCsu) of swine (Sus scrofa domesticus) in culture passages. P2, P5, and P9 were used for MSCBMsu and P1, P2, and P3 for RPCsu obtained by thawing. The experimental groups were submitted to MTT, apoptosis and necrosis assays, comet test, and reactive substance measurements of thiobarbituric acid (TBARS), nitrite, reduced glutathione (GSH), and catalase. The MTT test curve showed a mean viability of 1.14±0.62 and 1.12±0.54, respectively, for MSCBMsu and RPCsu. The percentages of MSCBMsu and RPCsu were presented, respectively, for apoptosis, an irregular and descending behavior, and necrosis, ascending and irregular. The DNA damage index showed higher intensity among the MSCBMsu in the P5 and P9 passages (p<0.05). In the TBARS evaluation, there was variation among the lines of RPCsu and MSCBMsu, presenting the last most significant variations (p<0.05). In the nitrite values, we identified only among the lines, in the passages P1 and P2, with the highest averages displayed by the MSCBMsu lineage (p<0.05). The measurement of antioxidant system activity showed high standards, identifying differences only for GSH values, in the RPCsu lineage, in P3 (p<0.05). This study suggests that the maintenance of cell culture in the long term induces lower regulation of oxidative stress, and RPCsu presents higher genetic stability and lower oxidative stress than MSCBMsu during in vitro expansion.